Can insomnia be fatal? An Australian case of fatal familial insomnia
Abstract Fatal familial insomnia (FFI) is a rare prion disease with autosomal dominant inheritance. Currently, there is only one published case study of FFI in Australia. FFI is universally fatal, with the disease duration ranging from 8 to 72 months. Clinically, it manifests with disordered sleep–wake cycle, dysautonomia, motor disturbances and neuropsychiatric disorders. We describe a case of FFI detailing the investigative process, including the importance of sleep assessment and polysomnography in obtaining a diagnosis..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
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| Enthalten in: |
Internal Medicine Journal - 52(2022), 4, Seite 667-670 |
| Beteiligte Personen: |
Habteslassie, Daniel [VerfasserIn] |
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| BKL: |
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| Anmerkungen: |
© 2022 Royal Australasian College of Physicians |
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| Umfang: |
4 |
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| doi: |
10.1111/imj.15737 |
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| funding: |
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| 520 | |a Abstract Fatal familial insomnia (FFI) is a rare prion disease with autosomal dominant inheritance. Currently, there is only one published case study of FFI in Australia. FFI is universally fatal, with the disease duration ranging from 8 to 72 months. Clinically, it manifests with disordered sleep–wake cycle, dysautonomia, motor disturbances and neuropsychiatric disorders. We describe a case of FFI detailing the investigative process, including the importance of sleep assessment and polysomnography in obtaining a diagnosis. | ||
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