Paradoxical effect of SARS‐CoV‐2 infection in patients with immune thrombocytopenia
Summary Thrombocytopenia has been identified as a common complication of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection in the general population. In an attempt to determine the impact of coronavirus disease 2019 (COVID‐19) in patients with immune thrombocytopenia (ITP), a retrospective single‐centre study was performed. Thrombocytosis was observed in patients with chronic ITP after SARS‐CoV‐2 infection, frequently needing treatment adjustment or even discontinuation of therapy. Relapses and newly diagnosed cases showed a fast response after initial treatment compared to ITP. Reduced immune activity due to lymphopenia during COVID‐19 could explain this paradoxical effect, although further studies are needed..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:192 |
|---|---|
| Enthalten in: |
British Journal of Haematology - 192(2021), 6, Seite 973-977 |
| Beteiligte Personen: |
Cruz‐Benito, Beatriz [VerfasserIn] |
|---|
| BKL: |
|---|
| Anmerkungen: |
Copyright © 2021 John Wiley & Sons Ltd |
|---|
| Umfang: |
5 |
|---|
| doi: |
10.1111/bjh.17077 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
WLY002819082 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | WLY002819082 | ||
| 003 | DE-627 | ||
| 005 | 20230307122136.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230213s2021 xx |||||o 00| ||und c | ||
| 024 | 7 | |a 10.1111/bjh.17077 |2 doi | |
| 028 | 5 | 2 | |a BJH_BJH17077.xml |
| 035 | |a (DE-627)WLY002819082 | ||
| 035 | |a (WILEY)BJH17077 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 082 | 0 | 4 | |a 610 |q ASE |
| 084 | |a 44.86 |2 bkl | ||
| 100 | 1 | |a Cruz‐Benito, Beatriz |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Paradoxical effect of SARS‐CoV‐2 infection in patients with immune thrombocytopenia |
| 264 | 1 | |c 2021 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Copyright © 2021 John Wiley & Sons Ltd | ||
| 520 | |a Summary Thrombocytopenia has been identified as a common complication of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection in the general population. In an attempt to determine the impact of coronavirus disease 2019 (COVID‐19) in patients with immune thrombocytopenia (ITP), a retrospective single‐centre study was performed. Thrombocytosis was observed in patients with chronic ITP after SARS‐CoV‐2 infection, frequently needing treatment adjustment or even discontinuation of therapy. Relapses and newly diagnosed cases showed a fast response after initial treatment compared to ITP. Reduced immune activity due to lymphopenia during COVID‐19 could explain this paradoxical effect, although further studies are needed. | ||
| 700 | 1 | |a Rivas‐Pollmar, María I. |4 aut | |
| 700 | 1 | |a Álvarez Román, María T. |4 aut | |
| 700 | 1 | |a Trelles‐Martínez, Roberto |4 aut | |
| 700 | 1 | |a Martín‐Salces, Monica |4 aut | |
| 700 | 1 | |a Lázaro‐del Campo, Paula |4 aut | |
| 700 | 1 | |a Ramírez‐López, Andrés |4 aut | |
| 700 | 1 | |a García‐Barcenilla, Sara |4 aut | |
| 700 | 1 | |a Cebanu, Tamara |4 aut | |
| 700 | 1 | |a Acuña‐Butta, Paula |4 aut | |
| 700 | 1 | |a Monzón‐Manzano, Elena |4 aut | |
| 700 | 1 | |a González‐Zorrilla, Elena |4 aut | |
| 700 | 1 | |a Jiménez‐Yuste, Victor |4 aut | |
| 700 | 1 | |a Butta, Nora V. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t British Journal of Haematology |g 192(2021), 6, Seite 973-977 |w (DE-627)WLY002803046 |x 13652141 |7 nnns |
| 773 | 1 | 8 | |g volume:192 |g year:2021 |g number:6 |g pages:973-977 |g extent:5 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_WLY | ||
| 936 | b | k | |a 44.86 |q ASE |
| 951 | |a AR | ||
| 952 | |d 192 |j 2021 |e 6 |h 973-977 |g 5 | ||