Cell therapy clinical trial of BOXR1030 in GPC3 positive liver, squamous lung, Merkel cell cancer, and myxoid/round cell liposarcoma : A first-in-human, phase 1/2, dose escalation study of BOXR1030 T cells in subjects with advanced GPC3-positive solid tumors
| Medienart: |
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Klinische Studie| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
WHO International Clinical Trials Registry Platform - (2023) vom: 20. Juni Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
WHO International Clinical Trials Registry Platform (https://www.who.int/ictrp/en/), First posted: 29-09-2022, Last updated: 2023-06-29 |
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| ICTRP ID: |
ISRCTN15110275 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
WHO008699712 |
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| 245 | 1 | 0 | |a Cell therapy clinical trial of BOXR1030 in GPC3 positive liver, squamous lung, Merkel cell cancer, and myxoid/round cell liposarcoma |b A first-in-human, phase 1/2, dose escalation study of BOXR1030 T cells in subjects with advanced GPC3-positive solid tumors |
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| 650 | 4 | |a Medical Condition: Patients with advanced, unresectable liver, squamous lung, and Merkel cell cancer, and myxoid/round cell liposarcoma that have tumor that is positive for GPC3 protein Cancer Histologically confirmed advanced unresectable or metastatic hepatocellular carcinoma (HCC), squamous cell carcinoma (SCC) of the lung, myxoid/round cell liposarcoma, or Merkel cell carcinoma (MCC) with GPC3 overexpression by IHC, with a cytoplasmic/membranous H-score >30 | |
| 650 | 4 | |a Study Type: Interventional | |
| 650 | 4 | |a Phase: Phase 1/Phase 2 | |
| 650 | 4 | |a Recruitment Status: Recruiting | |
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