A new ratiometric fluorescent probe for rapid and highly selective detection of Cysteine in bovine serum
As one of the most fundamental thiol compounds in the human body, cysteine (Cys) is involved in maintaining redox balance. Abnormal Cys levels can lead to various diseases. In this work, we successfully synthesized a fluorescent probe (CTBA) that can specifically detect Cys using acrylate as the reaction site, and CTBA has met the selectivity and anti-interference for Cys detection under optimized conditions. The linear range for Cys detection is between 0.05 and 100 μM and the detection limit is 0.0381 μM. Finally, this probe is used to detect the Cys content in three bovine serum samples and the test results are satisfactory. Graphical abstract.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
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| Enthalten in: |
Analytical sciences - 40(2024), 4 vom: 15. Feb., Seite 765-772 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Changjian [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Anmerkungen: |
© The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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| doi: |
10.1007/s44211-024-00516-8 |
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| funding: |
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| 520 | |a As one of the most fundamental thiol compounds in the human body, cysteine (Cys) is involved in maintaining redox balance. Abnormal Cys levels can lead to various diseases. In this work, we successfully synthesized a fluorescent probe (CTBA) that can specifically detect Cys using acrylate as the reaction site, and CTBA has met the selectivity and anti-interference for Cys detection under optimized conditions. The linear range for Cys detection is between 0.05 and 100 μM and the detection limit is 0.0381 μM. Finally, this probe is used to detect the Cys content in three bovine serum samples and the test results are satisfactory. Graphical abstract | ||
| 650 | 4 | |a Ratiometric fluorescent probe |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Acrylate |7 (dpeaa)DE-He213 | |
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| 700 | 1 | |a Ji, Peng |4 aut | |
| 700 | 1 | |a Liu, Xin |4 aut | |
| 700 | 1 | |a Feng, Guodong |4 aut | |
| 700 | 1 | |a Song, Zhiguang |4 aut | |
| 700 | 1 | |a Guo, Yupeng |4 aut | |
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