Supine Hypertension and Extreme Reverse Dipping Phenomenon Decades after Kidney Transplantation: A Case Report

Background Supine hypertension, a consequence of autonomic neuropathy, is a rarely recognized pathological condition. Reported diseases in the background are pure autonomic failure, multiple system atrophy, Parkinson’s disease, diabetes and different autoimmune disorders. Methods In our case report we present a case of supine hypertension which developed in a patient decades after kidney transplantation. The patient was followed for 25 months and we demonstrate the effect of the modification of antihypertensive medications. Results At the time of the diagnosis supine hypertension appeared immediately after laying down (office sitting Blood Pressure (BP): 143/101 mmHg; office supine BP: 171/113 mmHg) and on Ambulatory Blood Pressure Monitoring (ABPM) extreme reverse dipping was registered (daytime BP: 130/86 mmHg, nighttime BP: 175/114 mmHg). After the modification of the antihypertensive medications, both office supine BP (office sitting BP: 127/92 mmHg; office supine BP: 138/100 mmHg) and on ABPM nighttime BP improved markedly (daytime BP: 135/92 mmHg, nighttime BP: 134/90 mmHg). Conclusion In conclusions, our case report points out that autonomic neuropathy-caused supine hypertension and extreme reverse dipping can develop in chronic kidney disease, after kidney transplantation. The modification of the antihypertensive medications can slowly restore this pathological condition..

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:26

Enthalten in:

Artery research - 26(2020), 3 vom: 07. Juni, Seite 183-186

Sprache:

Englisch

Beteiligte Personen:

Batta, Dóra [VerfasserIn]
Kőrösi, Beáta [VerfasserIn]
Nemcsik, János [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

Ambulatory blood pressure monitoring
Autonomic neuropathy
Central hemodynamic parameters
Orthostatic hypotension
Reverse dipping
Supine hypertension

Anmerkungen:

© Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020

doi:

10.2991/artres.k.200603.002

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

SPR05472693X