Continuous and repeat metabolic measurements compared between post-cardiothoracic surgery and critical care patients
Objective Using a system, which accuracy is equivalent to the gold standard Douglas Bag (DB) technique for measuring oxygen consumption ($ VO_{2} $), carbon dioxide generation ($ VCO_{2} $), and respiratory quotient (RQ), we aimed to continuously measure these metabolic indicators and compare the values between post-cardiothoracic surgery and critical care patients. Methods This was a prospective, observational study conducted at a suburban, quaternary care teaching hospital. Age 18 years or older patients who underwent mechanical ventilation were enrolled. Results We included 4 post-surgery and 6 critical care patients. Of those, 3 critical care patients died. The longest measurement reached to 12 h and 15 min and 50 cycles of repeat measurements were performed. $ VO_{2} $ of the post-surgery patients were 234 ± 14, 262 ± 27, 212 ± 16, and 192 ± 20 mL/min, and those of critical care patients were 122 ± 20, 189 ± 9, 191 ± 7, 191 ± 24, 212 ± 12, and 135 ± 21 mL/min, respectively. The value of $ VO_{2} $ was more variable in the post-surgery patients and the range of each patient was 44, 126, 71, and 67, respectively. SOFA scores were higher in non-survivors and there were negative correlations of RQ with SOFA. Conclusions We developed an accurate system that enables continuous and repeat measurements of $ VO_{2} $, $ VCO_{2} $, and RQ. Critical care patients may have less activity in metabolism represented by less variable values of $ VO_{2} $ and $ VCO_{2} $ over time as compared to those of post-cardiothoracic surgery patients. Additionally, an alteration of these values may mean a systemic distinction of the metabolism of critically ill patients..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
BMC pulmonary medicine - 23(2023), 1 vom: 16. Okt. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shinozaki, Koichiro [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Carbon dioxide generation |
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| Anmerkungen: |
© The Author(s) 2023 |
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| doi: |
10.1186/s12890-023-02657-4 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 100 | 1 | |a Shinozaki, Koichiro |e verfasserin |4 aut | |
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| 520 | |a Objective Using a system, which accuracy is equivalent to the gold standard Douglas Bag (DB) technique for measuring oxygen consumption ($ VO_{2} $), carbon dioxide generation ($ VCO_{2} $), and respiratory quotient (RQ), we aimed to continuously measure these metabolic indicators and compare the values between post-cardiothoracic surgery and critical care patients. Methods This was a prospective, observational study conducted at a suburban, quaternary care teaching hospital. Age 18 years or older patients who underwent mechanical ventilation were enrolled. Results We included 4 post-surgery and 6 critical care patients. Of those, 3 critical care patients died. The longest measurement reached to 12 h and 15 min and 50 cycles of repeat measurements were performed. $ VO_{2} $ of the post-surgery patients were 234 ± 14, 262 ± 27, 212 ± 16, and 192 ± 20 mL/min, and those of critical care patients were 122 ± 20, 189 ± 9, 191 ± 7, 191 ± 24, 212 ± 12, and 135 ± 21 mL/min, respectively. The value of $ VO_{2} $ was more variable in the post-surgery patients and the range of each patient was 44, 126, 71, and 67, respectively. SOFA scores were higher in non-survivors and there were negative correlations of RQ with SOFA. Conclusions We developed an accurate system that enables continuous and repeat measurements of $ VO_{2} $, $ VCO_{2} $, and RQ. Critical care patients may have less activity in metabolism represented by less variable values of $ VO_{2} $ and $ VCO_{2} $ over time as compared to those of post-cardiothoracic surgery patients. Additionally, an alteration of these values may mean a systemic distinction of the metabolism of critically ill patients. | ||
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| 650 | 4 | |a Oxygen consumption |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Carbon dioxide generation |7 (dpeaa)DE-He213 | |
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| 700 | 1 | |a Yu, Pey-Jen |4 aut | |
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| 700 | 1 | |a Rolston, Daniel M. |4 aut | |
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| 700 | 1 | |a Li, Timmy |4 aut | |
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| 700 | 1 | |a Saeki, Kota |4 aut | |
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| 700 | 1 | |a Okuma, Yu |4 aut | |
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| 700 | 1 | |a Hayashida, Kei |4 aut | |
| 700 | 1 | |a Aoki, Tomoaki |4 aut | |
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| 700 | 1 | |a Molmenti, Ernesto P. |4 aut | |
| 700 | 1 | |a Lampe, Joshua W. |4 aut | |
| 700 | 1 | |a Becker, Lance B. |4 aut | |
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