Non-Arthroplasty Surgical Treatments for Knee Osteoarthritis and Cartilage Damage: a 10 Year Update
Abstract Osteoarthritis is a chronic, degenerative disease leading to pain and decreased functionality in millions of people in the United States every year. The knee joint is the most commonly affected joint and has a direct impact on patients’ mobility and ability to perform activities of daily living. Osteoarthritis is treated conservatively with a variety of modalities, including anti-inflammatories, physical therapy, corticosteroid, viscosupplementation, and platelet-rich plasma injections. The gold standard surgical treatment for eligible patients with severe osteoarthritis is total or unicompartmental knee arthroplasty. However, many patients may not be candidates for, or may opt to delay, knee replacement but still require surgery. In these cases, patients may receive lavage and debridement, microfracture, osteochondral allograft or autograft transplantation, autologous chondrocyte implantation, or high tibial osteotomy. This review will provide an overview of literature surrounding these non-arthroplasty, surgical treatment options for treating cartilage defects and knee osteoarthritis. In addition to being evaluated based on efficacy and discussing the ideal patient populations for each procedure, these surgeries will be compared in terms of cost-effectiveness and impact on quality of life..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
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| Enthalten in: |
SN comprehensive clinical medicine - 5(2023), 1 vom: 02. Sept. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yin, Sophia Sarang Shin [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
Autologous chondrocyte implantation |
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| Anmerkungen: |
© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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| doi: |
10.1007/s42399-023-01554-5 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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SPR052971236 |
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| 520 | |a Abstract Osteoarthritis is a chronic, degenerative disease leading to pain and decreased functionality in millions of people in the United States every year. The knee joint is the most commonly affected joint and has a direct impact on patients’ mobility and ability to perform activities of daily living. Osteoarthritis is treated conservatively with a variety of modalities, including anti-inflammatories, physical therapy, corticosteroid, viscosupplementation, and platelet-rich plasma injections. The gold standard surgical treatment for eligible patients with severe osteoarthritis is total or unicompartmental knee arthroplasty. However, many patients may not be candidates for, or may opt to delay, knee replacement but still require surgery. In these cases, patients may receive lavage and debridement, microfracture, osteochondral allograft or autograft transplantation, autologous chondrocyte implantation, or high tibial osteotomy. This review will provide an overview of literature surrounding these non-arthroplasty, surgical treatment options for treating cartilage defects and knee osteoarthritis. In addition to being evaluated based on efficacy and discussing the ideal patient populations for each procedure, these surgeries will be compared in terms of cost-effectiveness and impact on quality of life. | ||
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| 650 | 4 | |a Autologous chondrocyte implantation |7 (dpeaa)DE-He213 | |
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| 650 | 4 | |a High tibial osteotomy |7 (dpeaa)DE-He213 | |
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