Emergence of melioidosis in Brazil: a case series
Background Melioidosis is a serious disease caused by the bacterium Burkholderia pseudomallei which affects humans and animals. It results in a wide spectrum of clinical manifestations, mainly in the respiratory tract, progressing to septic shock and death. Case presentation Herein, we present a series of seven patients (median age: 41 years) with confirmed melioidosis, treated at a public hospital in Piauí State, Brazil between 2019 and 2021. The most common clinical presentations were fever, cough, pneumonia, and abdominal pain. The mean duration of antibacterial therapy with 1 g of meropenem was 28.6 ± 1.1 days. Six patients recovered and one died. The mean hospitalization time was 51.0 ± 39.2 days. Conclusions Melioidosis is an emerging infectious disease in Brazil. Health professionals in endemic areas need to be aware of the clinical presentation and appropriate clinical management of the disease because early diagnosis and early initiation of antibiotic therapy can be life-saving..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
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| Enthalten in: |
Journal of medical case reports - 17(2023), 1 vom: 23. Aug. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Velôso, Dilbert Silva [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
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| Anmerkungen: |
© The Author(s) 2023 |
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| doi: |
10.1186/s13256-023-04093-8 |
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| funding: |
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SPR052831760 |
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| 100 | 1 | |a Velôso, Dilbert Silva |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Emergence of melioidosis in Brazil: a case series |
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| 520 | |a Background Melioidosis is a serious disease caused by the bacterium Burkholderia pseudomallei which affects humans and animals. It results in a wide spectrum of clinical manifestations, mainly in the respiratory tract, progressing to septic shock and death. Case presentation Herein, we present a series of seven patients (median age: 41 years) with confirmed melioidosis, treated at a public hospital in Piauí State, Brazil between 2019 and 2021. The most common clinical presentations were fever, cough, pneumonia, and abdominal pain. The mean duration of antibacterial therapy with 1 g of meropenem was 28.6 ± 1.1 days. Six patients recovered and one died. The mean hospitalization time was 51.0 ± 39.2 days. Conclusions Melioidosis is an emerging infectious disease in Brazil. Health professionals in endemic areas need to be aware of the clinical presentation and appropriate clinical management of the disease because early diagnosis and early initiation of antibiotic therapy can be life-saving. | ||
| 650 | 4 | |a Melioidosis |7 (dpeaa)DE-He213 | |
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| 700 | 1 | |a da Silva, Samuel Pinheiro |4 aut | |
| 700 | 1 | |a de Coelho, Conceição Maria Sousa |4 aut | |
| 700 | 1 | |a Parente, José Miguel Luz |4 aut | |
| 700 | 1 | |a Veloso, Thaline Alves Elias |4 aut | |
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| 700 | 1 | |a Sampaio, Caroline Torres |4 aut | |
| 700 | 1 | |a de Freitas, Maria Fátima Alencar Bezerra |4 aut | |
| 700 | 1 | |a Rolim, Dionne Bezerra |4 aut | |
| 700 | 1 | |a de Lemos, Elba Regina Sampaio |4 aut | |
| 700 | 1 | |a Horta, Marco Aurélio Pereira |0 (orcid)0000-0003-4117-5379 |4 aut | |
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