Meningitis-retention syndrome: a review and update of an unrecognized clinical condition
Objectives We summarized the clinical and radiological characteristics of meningitis-retention syndrome (MRS), its therapeutic options, and urological outcome, to better understand the pathogenesis of this syndrome and to evaluate the effectiveness of corticosteroids in reducing the period of urinary retention. Methods We reported a new case of MRS in a male adolescent. We also reviewed the previously 28 reported cases of MRS, collected from inception up to September 2022. Results MRS is characterized by aseptic meningitis and urinary retention. The mean length of the interval between the onset of the neurological signs and the urinary retention was 6.4 days. In most cases, no pathogens were isolated in cerebrospinal fluid, except for 6 cases in which Herpesviruses were detected. The urodynamic study resulted in a detrusor underactivity, with a mean period for urination recovery of 4.5 weeks, regardless of therapies. Discussion Neurophysiological studies and electromyographic examination are not pathological, distinguishing MRS from polyneuropathies. Although there are no encephalitic symptoms or signs, and the magnetic resonance is often normal, MRS may represent a mild form of acute disseminated encephalomyelitis, without radiological detectable medullary involvement, due to the prompt use of steroids. It is believed that MRS is a self-limited disease, and no evidence suggests the effectiveness of steroids, antibiotics, and antiviral treatment in its clinical course..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
|---|---|
| Enthalten in: |
Neurological sciences - 44(2023), 6 vom: 03. März, Seite 1949-1957 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Pellegrino, Francesco [VerfasserIn] |
|---|
| Links: |
Volltext [kostenfrei] |
|---|
| Themen: |
Acute disseminated encephalomyelopathy |
|---|
| Anmerkungen: |
© The Author(s) 2023 |
|---|
| doi: |
10.1007/s10072-023-06704-0 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
SPR052399133 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR052399133 | ||
| 003 | DE-627 | ||
| 005 | 20230726102412.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230726s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10072-023-06704-0 |2 doi | |
| 035 | |a (DE-627)SPR052399133 | ||
| 035 | |a (SPR)s10072-023-06704-0-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Pellegrino, Francesco |e verfasserin |0 (orcid)0000-0002-4353-8324 |4 aut | |
| 245 | 1 | 0 | |a Meningitis-retention syndrome: a review and update of an unrecognized clinical condition |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © The Author(s) 2023 | ||
| 520 | |a Objectives We summarized the clinical and radiological characteristics of meningitis-retention syndrome (MRS), its therapeutic options, and urological outcome, to better understand the pathogenesis of this syndrome and to evaluate the effectiveness of corticosteroids in reducing the period of urinary retention. Methods We reported a new case of MRS in a male adolescent. We also reviewed the previously 28 reported cases of MRS, collected from inception up to September 2022. Results MRS is characterized by aseptic meningitis and urinary retention. The mean length of the interval between the onset of the neurological signs and the urinary retention was 6.4 days. In most cases, no pathogens were isolated in cerebrospinal fluid, except for 6 cases in which Herpesviruses were detected. The urodynamic study resulted in a detrusor underactivity, with a mean period for urination recovery of 4.5 weeks, regardless of therapies. Discussion Neurophysiological studies and electromyographic examination are not pathological, distinguishing MRS from polyneuropathies. Although there are no encephalitic symptoms or signs, and the magnetic resonance is often normal, MRS may represent a mild form of acute disseminated encephalomyelitis, without radiological detectable medullary involvement, due to the prompt use of steroids. It is believed that MRS is a self-limited disease, and no evidence suggests the effectiveness of steroids, antibiotics, and antiviral treatment in its clinical course. | ||
| 650 | 4 | |a Meningitis-retention syndrome |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Urinary retention |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Acute disseminated encephalomyelopathy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Aseptic meningitis |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Funiciello, Elisa |4 aut | |
| 700 | 1 | |a Pruccoli, Giulia |4 aut | |
| 700 | 1 | |a Silvestro, Erika |4 aut | |
| 700 | 1 | |a Scolfaro, Carlo |4 aut | |
| 700 | 1 | |a Mignone, Federica |4 aut | |
| 700 | 1 | |a Tocchet, Aba |4 aut | |
| 700 | 1 | |a Roasio, Luca |4 aut | |
| 700 | 1 | |a Garazzino, Silvia |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Neurological sciences |d Milano : Springer, 2000 |g 44(2023), 6 vom: 03. März, Seite 1949-1957 |w (DE-627)SPR008581010 |w (DE-600)1481772-X |x 1590-3478 |7 nnns |
| 773 | 1 | 8 | |g volume:44 |g year:2023 |g number:6 |g day:03 |g month:03 |g pages:1949-1957 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s10072-023-06704-0 |z kostenfrei |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 951 | |a AR | ||
| 952 | |d 44 |j 2023 |e 6 |b 03 |c 03 |h 1949-1957 | ||