Impact of SARS-CoV2 infection on mortality and hospitalization in nursing home residents during the “Omicron era”
Background Widespread vaccination and emergence of less aggressive SARS-CoV2 variants may have blunted the unfavourable outcomes of COVID-19 in nursing home (NH) residents. We analysed the course of COVID-19 epidemic in NHs of Florence, Italy, during the “Omicron era” and investigated the independent effect of SARS-CoV2 infection on death and hospitalization risk. Methods Weekly SARS-CoV2 infection rates between November 2021 and March 2022 were calculated. Detailed clinical data were collected in a sample of NHs. Results Among 2044 residents, 667 SARS-CoV2 cases were confirmed. SARS-CoV2 incidence sharply increased during the Omicron era. Mortality rates did not differ between SARS-CoV2-positive (6.9%) and SARS-CoV2-negative residents (7.3%, p = 0.71). Chronic obstructive pulmonary disease and poor functional status, but not SARS-CoV2 infection independently predicted death and hospitalization. Conclusions Despite that SARS-CoV2 incidence increased during the Omicron era, SARS-CoV2 infection was not a significant predictor of hospitalization and death in the NH setting..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
|---|---|
| Enthalten in: |
Aging clinical and experimental research - 35(2023), 6 vom: 27. Apr., Seite 1393-1399 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Bulgaresi, Matteo [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023 |
|---|
| doi: |
10.1007/s40520-023-02415-w |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
SPR051576236 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR051576236 | ||
| 003 | DE-627 | ||
| 005 | 20230522064615.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230522s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s40520-023-02415-w |2 doi | |
| 035 | |a (DE-627)SPR051576236 | ||
| 035 | |a (SPR)s40520-023-02415-w-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Bulgaresi, Matteo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Impact of SARS-CoV2 infection on mortality and hospitalization in nursing home residents during the “Omicron era” |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023 | ||
| 520 | |a Background Widespread vaccination and emergence of less aggressive SARS-CoV2 variants may have blunted the unfavourable outcomes of COVID-19 in nursing home (NH) residents. We analysed the course of COVID-19 epidemic in NHs of Florence, Italy, during the “Omicron era” and investigated the independent effect of SARS-CoV2 infection on death and hospitalization risk. Methods Weekly SARS-CoV2 infection rates between November 2021 and March 2022 were calculated. Detailed clinical data were collected in a sample of NHs. Results Among 2044 residents, 667 SARS-CoV2 cases were confirmed. SARS-CoV2 incidence sharply increased during the Omicron era. Mortality rates did not differ between SARS-CoV2-positive (6.9%) and SARS-CoV2-negative residents (7.3%, p = 0.71). Chronic obstructive pulmonary disease and poor functional status, but not SARS-CoV2 infection independently predicted death and hospitalization. Conclusions Despite that SARS-CoV2 incidence increased during the Omicron era, SARS-CoV2 infection was not a significant predictor of hospitalization and death in the NH setting. | ||
| 650 | 4 | |a COVID-19 |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Vaccination |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Immunization |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Functional status |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Older adults |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Rivasi, Giulia |0 (orcid)0000-0002-2736-2242 |4 aut | |
| 700 | 1 | |a Tarantini, Francesca |4 aut | |
| 700 | 1 | |a Espinoza Tofalos, Sofia |4 aut | |
| 700 | 1 | |a Del Re, Lorenzo Maria |4 aut | |
| 700 | 1 | |a Salucci, Caterina |4 aut | |
| 700 | 1 | |a Turrin, Giada |4 aut | |
| 700 | 1 | |a Barucci, Riccardo |4 aut | |
| 700 | 1 | |a Bandinelli, Chiara |4 aut | |
| 700 | 1 | |a Fattorini, Letizia |4 aut | |
| 700 | 1 | |a Borchi, Daniele |4 aut | |
| 700 | 1 | |a Betti, Marta |4 aut | |
| 700 | 1 | |a Checchi, Saverio |4 aut | |
| 700 | 1 | |a Baggiani, Lorenzo |4 aut | |
| 700 | 1 | |a Collini, Francesca |4 aut | |
| 700 | 1 | |a Lorini, Chiara |4 aut | |
| 700 | 1 | |a Bonaccorsi, Guglielmo |4 aut | |
| 700 | 1 | |a Ungar, Andrea |4 aut | |
| 700 | 1 | |a Mossello, Enrico |4 aut | |
| 700 | 1 | |a Benvenuti, Enrico |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Aging clinical and experimental research |d Berlin : Heidelberg : Springer, 2002 |g 35(2023), 6 vom: 27. Apr., Seite 1393-1399 |w (DE-627)SPR036583642 |w (DE-600)2119282-0 |x 1720-8319 |7 nnns |
| 773 | 1 | 8 | |g volume:35 |g year:2023 |g number:6 |g day:27 |g month:04 |g pages:1393-1399 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s40520-023-02415-w |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 951 | |a AR | ||
| 952 | |d 35 |j 2023 |e 6 |b 27 |c 04 |h 1393-1399 | ||