Genetic Expression of CYP2B6 Gene in Phenobarbitone Responder and Non-responder Neonates
Abstract Quantitative real-time polymerase chain reaction for identifying CYP2B6 gene expression was done on blood samples of 30 phenobarbitone responder and 30 non-responder neonates with seizures. CYP2B6 was observed to be significantly down regulated among phenobarbitone non-responders as compared to phenobarbitone responders (Mean (SD) ΔCt 17.97 (1.19) vs 15.40 (1.83); P<0.001)..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
|---|---|
| Enthalten in: |
Indian Pediatrics - 60(2023), 3 vom: März, Seite 235-236 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Yadav, Kritika [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| Themen: |
|---|
| Anmerkungen: |
© Indian Academy of Pediatrics 2023 |
|---|
| doi: |
10.1007/s13312-023-2843-1 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
SPR049890816 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR049890816 | ||
| 003 | DE-627 | ||
| 005 | 20230330180721.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230330s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s13312-023-2843-1 |2 doi | |
| 035 | |a (DE-627)SPR049890816 | ||
| 035 | |a (SPR)s13312-023-2843-1-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Yadav, Kritika |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Genetic Expression of CYP2B6 Gene in Phenobarbitone Responder and Non-responder Neonates |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © Indian Academy of Pediatrics 2023 | ||
| 520 | |a Abstract Quantitative real-time polymerase chain reaction for identifying CYP2B6 gene expression was done on blood samples of 30 phenobarbitone responder and 30 non-responder neonates with seizures. CYP2B6 was observed to be significantly down regulated among phenobarbitone non-responders as compared to phenobarbitone responders (Mean (SD) ΔCt 17.97 (1.19) vs 15.40 (1.83); P<0.001). | ||
| 650 | 4 | |a Gene expression |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Drug resistance |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Batra, Prerna |4 aut | |
| 700 | 1 | |a Bhaskar, Vikram |4 aut | |
| 700 | 1 | |a Aggarwal, Anju |4 aut | |
| 700 | 1 | |a Banerjee, Basu Dev |4 aut | |
| 700 | 1 | |a Kumar, Harendar |4 aut | |
| 700 | 1 | |a Sharma, Tusha |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Indian Pediatrics |d Springer-Verlag, 2010 |g 60(2023), 3 vom: März, Seite 235-236 |w (DE-627)SPR031274943 |7 nnns |
| 773 | 1 | 8 | |g volume:60 |g year:2023 |g number:3 |g month:03 |g pages:235-236 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s13312-023-2843-1 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 951 | |a AR | ||
| 952 | |d 60 |j 2023 |e 3 |c 03 |h 235-236 | ||