Evaluation of Retinal Vascularity Index in Patients with COVID-19: A Case–Control Study
Introduction The purpose of this study was to evaluate the impact of COVID-19 infection on retinal microvasculature by topographically mapping the retinal arteriole-to-venule ratio (AVR). Methods In a comparative cross-sectional case–control study, fundus photos were obtained in COVID-19-infected patients and healthy controls. AVT was measured over 16 points across the retina using retinal vascularity index (RVI)—a novel semi-automated computerized parameter based on retinal vasculature. Results A total of 51 COVID-19-positive patients and 65 healthy controls were enrolled in the study. Overall, the mean RVI of all 16 points across the retina was 0.34 ± 0.02 in patients with COVID-19 and 0.33 ± 0.02 in control subjects (p = 0.64). Out of the 16 points being measured, three points had a statistically significant greater value in patients with COVID compared to normal controls. Conclusion Localised greater RVI values were found in some of the points in COVID-19-positive patients, which likely indicates a more focal change of the vasculature..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Ophthalmology and therapy - 12(2022), 2 vom: 22. Dez., Seite 879-894 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wenting, Sandy Zhou [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
AVR |
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| Anmerkungen: |
© The Author(s) 2022 |
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| doi: |
10.1007/s40123-022-00630-8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
SPR049676326 |
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| 520 | |a Introduction The purpose of this study was to evaluate the impact of COVID-19 infection on retinal microvasculature by topographically mapping the retinal arteriole-to-venule ratio (AVR). Methods In a comparative cross-sectional case–control study, fundus photos were obtained in COVID-19-infected patients and healthy controls. AVT was measured over 16 points across the retina using retinal vascularity index (RVI)—a novel semi-automated computerized parameter based on retinal vasculature. Results A total of 51 COVID-19-positive patients and 65 healthy controls were enrolled in the study. Overall, the mean RVI of all 16 points across the retina was 0.34 ± 0.02 in patients with COVID-19 and 0.33 ± 0.02 in control subjects (p = 0.64). Out of the 16 points being measured, three points had a statistically significant greater value in patients with COVID compared to normal controls. Conclusion Localised greater RVI values were found in some of the points in COVID-19-positive patients, which likely indicates a more focal change of the vasculature. | ||
| 650 | 4 | |a Retinal vascularity index |7 (dpeaa)DE-He213 | |
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| 700 | 1 | |a Shrivastav, Ankita |4 aut | |
| 700 | 1 | |a Gilada, Trupti |4 aut | |
| 700 | 1 | |a Le Ng, Xin |4 aut | |
| 700 | 1 | |a Ng, Sean |4 aut | |
| 700 | 1 | |a Chua, Chun Hau |4 aut | |
| 700 | 1 | |a Dutt, Shibjash |4 aut | |
| 700 | 1 | |a Natarajan, Sundaram |4 aut | |
| 700 | 1 | |a Agrawal, Rupesh |0 (orcid)0000-0002-6662-5850 |4 aut | |
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