Magnetic resonance imaging features of post-COVID-19 regional and invasive sino-nasal mucormycosis

Background Sino-nasal mucormycosis is an opportunistic, invasive fungal disease which has shown a rising trend in the setting of COVID-19. The objective of this study is to document and analyze demographic data, clinical presentation and MR imaging spectra for early detection and management of post-COVID-19 sino-nasal mucormycosis. Results Sixty-two cases of sino-nasal mucormycosis were enrolled in this study; their mean age was 50.65 ± 8.25 years, with significant female predominance. Nine patients (14.5%) had active COVID-19 and 53 (85.5%) were recent COVID-19 cases. Sixty patients have not received COVID-19 vaccine. The mean duration from the initial COVID-19 laboratory confirmation to the detection of sino-nasal mucormycosis was 25.7 +/− 4.6 days. Thirty-five patients (56.5%) were kept in the hospital for COVID management and 4 of them received intensive care unit (ICU) treatment. Twenty-seven patients (43.5%) were treated in home isolation. Corticosteroids were administered in 48 cases (77.4%). Twenty-nine patients (46.8%) had been given oxygen for an average time of 11.2 ± 4.15 days. Diabetes was found in 56 cases (90.3%). The most common clinical symptoms were headache, seen in 52 patients (83.87%). The ethmoid sinus was the most common paranasal sinus involved in our study, seen in 47 cases (75.81%). In 36 cases (58%), multiple sinuses were involved. MRI staging according to the extent of regional involvement. Stage 1 seen in 2 cases (3.23%), stage 2 in 13 cases (20.97%), stage 3 in 35 cases (56.45%) and stage 4 in 12 cases (19.35%). Conclusions MRI shows a spectrum of findings in sino-nasal mucormycosis. Imaging plays a major role in staging and assessing the extent of involvement and complications. In light of this, mortality and morbidity can be dramatically decreased with adequate evaluation and therapy..

Medienart:	E-Artikel

Erscheinungsjahr:	2022
Erschienen:	2022

Enthalten in:	Zur Gesamtaufnahme - volume:53
Enthalten in:	The Egyptian Journal of Radiology and Nuclear Medicine - 53(2022), 1 vom: 28. Nov.

Sprache:	Englisch

Beteiligte Personen:	Abd El Megid, Ahmed Gamil Ibrahim [VerfasserIn] AbdelHamid, Ghada Adel [VerfasserIn] Abd Elbary, Mohamed El-Sayed [VerfasserIn] Ghonimi, Nesma A. M. [VerfasserIn] Elagrody, Ahmed I. [VerfasserIn] Abd Elhamed, Marwa Elsayed [VerfasserIn]

Links:	Volltext [kostenfrei]

Themen:	COVID-19 MRI Mucormycosis

Anmerkungen:	© The Author(s) 2022

doi:	10.1186/s43055-022-00930-w

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	SPR048755567