Risk of Hospitalization in Under-five Children With Community-Acquired Pneumonia: A Multicentric Prospective Cohort Study
Objective To evaluate factors associated with risk of hospitalization in children with community-acquired pneumonia (CAP). Design Prospective cohort study. Setting Multi-site hospital based study. Intervention A separate acute respiratory tract infection (ARI) treatment unit (ATU) was established. The revised WHO case definition for ARI was used across all the study sites to ensure uniformity in management of ARI patients (2–59 months). Clinical history, examination findings and investigations of enrolled patients were recorded on a predesigned case record form. Children were followed up at 1 week (± 1 day). Main outcome measure Risk factors for hospitalization among pneumonia patients. Results A total of 7026 children with the diagnosis of ARI were enrolled. Pneumonia was diagnosed in 938 (13.4%) patients (median (IQR) age: 15 (8, 25) months; 63.5% boys). Hospitalization was needed in 56.8% of pneumonia patients. On multivariate analysis, factors associated with risk of hospitalization were: Oxygen saturation on pulse oximetry ($ SpO_{2} $) <92% in room air (OR 7.04; 95% CI 1.6, 30.8, >0.5 ng/mL (OR: 7.5, 95% CI: 1.0, 57.7, P=0.05), and lower weight for height z-score (OR 0.8; 95 % CI: 0.6, 0.9, P=0.02). Conclusion Present study found $ SpO_{2} $ <92% at room air, serum procalcitonin level >0.5 ng/mL and lower weight for height z-score to be predictors for risk of hospitalization in under-five children presenting with community acquired pneumonia. These factors can be utilized to assess a child with CAP regarding the need of hospitalization..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
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| Enthalten in: |
Indian Pediatrics - 58(2021), 11 vom: Nov., Seite 1019-1023 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bhat, Javeed Iqbal [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
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| Anmerkungen: |
© Indian Academy of Pediatrics 2021 |
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| doi: |
10.1007/s13312-021-2366-4 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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SPR045724075 |
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| 520 | |a Objective To evaluate factors associated with risk of hospitalization in children with community-acquired pneumonia (CAP). Design Prospective cohort study. Setting Multi-site hospital based study. Intervention A separate acute respiratory tract infection (ARI) treatment unit (ATU) was established. The revised WHO case definition for ARI was used across all the study sites to ensure uniformity in management of ARI patients (2–59 months). Clinical history, examination findings and investigations of enrolled patients were recorded on a predesigned case record form. Children were followed up at 1 week (± 1 day). Main outcome measure Risk factors for hospitalization among pneumonia patients. Results A total of 7026 children with the diagnosis of ARI were enrolled. Pneumonia was diagnosed in 938 (13.4%) patients (median (IQR) age: 15 (8, 25) months; 63.5% boys). Hospitalization was needed in 56.8% of pneumonia patients. On multivariate analysis, factors associated with risk of hospitalization were: Oxygen saturation on pulse oximetry ($ SpO_{2} $) <92% in room air (OR 7.04; 95% CI 1.6, 30.8, >0.5 ng/mL (OR: 7.5, 95% CI: 1.0, 57.7, P=0.05), and lower weight for height z-score (OR 0.8; 95 % CI: 0.6, 0.9, P=0.02). Conclusion Present study found $ SpO_{2} $ <92% at room air, serum procalcitonin level >0.5 ng/mL and lower weight for height z-score to be predictors for risk of hospitalization in under-five children presenting with community acquired pneumonia. These factors can be utilized to assess a child with CAP regarding the need of hospitalization. | ||
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| 700 | 1 | |a Ahad, Ridwana |e verfasserin |4 aut | |
| 700 | 1 | |a Das, Rashmi R. |e verfasserin |4 aut | |
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