Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All
Abstract COVID-19 is a new infectious disease causing severe respiratory failure and death for which optimal treatment is currently unclear. Many therapies have been proven to be ineffective; however, promising findings related to corticosteroid therapy have been published. Analysis of published data including in this issue suggests that therapy with corticosteroids in the range of 6 mg of dexamethasone (or equivalent) per day likely has a positive effect in patients requiring mechanical ventilation but there remains considerable doubt in patients over the age of 70, in patients with diabetes and patients with milder disease. Clinicians must consider the individual potential risks and benefits of corticosteroid in patients with COVID-19 rather than routinely using them until more data is available..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
|---|---|
| Enthalten in: |
Infectious diseases and therapy - 9(2020), 4 vom: 16. Sept., Seite 701-705 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Waterer, Grant W. [VerfasserIn] |
|---|
| Links: |
Volltext [kostenfrei] |
|---|
| Themen: |
ARDS |
|---|
| doi: |
10.1007/s40121-020-00338-x |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
SPR042044162 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR042044162 | ||
| 003 | DE-627 | ||
| 005 | 20230519234052.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201122s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s40121-020-00338-x |2 doi | |
| 035 | |a (DE-627)SPR042044162 | ||
| 035 | |a (SPR)s40121-020-00338-x-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q ASE |
| 100 | 1 | |a Waterer, Grant W. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Abstract COVID-19 is a new infectious disease causing severe respiratory failure and death for which optimal treatment is currently unclear. Many therapies have been proven to be ineffective; however, promising findings related to corticosteroid therapy have been published. Analysis of published data including in this issue suggests that therapy with corticosteroids in the range of 6 mg of dexamethasone (or equivalent) per day likely has a positive effect in patients requiring mechanical ventilation but there remains considerable doubt in patients over the age of 70, in patients with diabetes and patients with milder disease. Clinicians must consider the individual potential risks and benefits of corticosteroid in patients with COVID-19 rather than routinely using them until more data is available. | ||
| 650 | 4 | |a ARDS |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Coronavirus |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Covid-19 |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pneumonia |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Precision medicine |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a RCT |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a SARS |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Therapy |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Rello, Jordi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Infectious diseases and therapy |d Heidelberg : Springer, 2012 |g 9(2020), 4 vom: 16. Sept., Seite 701-705 |w (DE-627)SPR032878133 |w (DE-600)2701611-0 |x 2193-6382 |7 nnns |
| 773 | 1 | 8 | |g volume:9 |g year:2020 |g number:4 |g day:16 |g month:09 |g pages:701-705 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s40121-020-00338-x |z kostenfrei |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 912 | |a SSG-OLC-PHA | ||
| 951 | |a AR | ||
| 952 | |d 9 |j 2020 |e 4 |b 16 |c 09 |h 701-705 | ||