A Conformational Isomer of Soulattrolide from the Stem Bark of Calophyllum symingtonianum and Its Antibacterial Activity
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
Natural product sciences - 24(2018), 1, Seite 47-53 |
| Beteiligte Personen: |
Susanti, Deny [Sonstige Person] |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2145723218 |
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| 245 | 1 | 0 | |a A Conformational Isomer of Soulattrolide from the Stem Bark of Calophyllum symingtonianum and Its Antibacterial Activity |
| 264 | 1 | |c 2018 | |
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| 508 | |a Callophylum symingtonianum (Guttiferae), an evergreen broad-leaved tree that usually grows in hill forests, can be found distributed in the Malay Peninsula. The barks, leaves, flowers and seeds is often used medicinally to treat diarrhea and rheumatism. In the present study, we isolated two inophyllum type coumarins, 12-O-ethylinophyllum D (1) and iso-soulattrolide (2) from the stembarks of C. symingtonianum together with their antibacterial activity. The compounds were isolated by chromatographic methods on a silica gel. The structures were established by spectroscopic methods including UV, IR, (1D and 2D) NMR and mass spectrometry as well as by comparison with several literature sources. The antibacterial activity of those compounds was tested using a disc-diffusion assay against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. Both compound exhibited mild inhibition against P. aeruginosa with both 111 μg/ml MIC value. Compound 2 also inhibits S. aureus with 25 μg/ml MIC value. | ||
| 700 | 1 | |a Susanti, Deny |4 oth | |
| 700 | 1 | |a Attoumani, Nissad |4 oth | |
| 700 | 1 | |a Taher, Muhammad |4 oth | |
| 700 | 1 | |a Rezali, Mohd Fazlin |4 oth | |
| 700 | 1 | |a Sohrab, Hossain |4 oth | |
| 700 | 1 | |a Hasan, Choudhury Mahmood |4 oth | |
| 700 | 1 | |a Zakaria, Zainul Amiruddin |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Natural product sciences |d Seoul : Soc., 1995 |g 24(2018), 1, Seite 47-53 |w (DE-627)219510652 |w (DE-600)1353188-8 |w (DE-576)435516280 |x 1226-3907 |7 nnns |
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