The Emerging Role of Ketamine in Acute Postoperative Pain Management

Purpose of Review Postoperative pain (POP) is among the most unpleasant experiences that patients face after surgery. Interest in and use of N-methyl-D-aspartate (NMDA) receptor antagonists for the management of POP has increased over the years with ketamine being the most popular drug of this class. Recent Findings Several randomized controlled trials found that the use of ketamine either alone or in combination with other medications leads to decreased postoperative pain and opioid consumption. However, there are other studies that have not found these benefits. The results as of now suggest that the role of intraoperative ketamine in postoperative pain control varies among different operative procedures. Summary While some studies have shown promise in ketamine’s potential use as a postoperative analgesic, there is still a great deal of proposed research and randomized controlled trials needed to deduce the most efficacious and tolerable form and dose of ketamine..

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Current pain and headache reports - 27(2023), 9 vom: 28. Juni, Seite 387-397

Sprache:

Englisch

Beteiligte Personen:

Edinoff, Amber N. [VerfasserIn]
Askins, Dorothy [VerfasserIn]
Bobo, Elena [VerfasserIn]
White, Kathryn L. [VerfasserIn]
Eswani, Zahaan [VerfasserIn]
Jackson, Eric D. [VerfasserIn]
Wenger, Danielle M. [VerfasserIn]
Kaye, Aaron J. [VerfasserIn]
Cornett., Elyse M. [VerfasserIn]
Kaye, Adam M. [VerfasserIn]
Kaye, Alan D. [VerfasserIn]

Links:

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BKL:

44.90$jNeurologie

Themen:

Acute pain
Ketamine
Opioids
Pain
Postoperative pain

Anmerkungen:

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s11916-023-01134-1

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2145268782

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