A $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure-based photoelectrochemical biosensor for neuron-specific enolase
Abstract An efficient photo-to-electrical signal is pivotal to photoelectrochemical (PEC) biosensors. In our work, a novel PEC biosensor was fabricated for the detection of neuron-specific enolase (NSE) based on a $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure. Due to the overlapping band potentials of the $ ZnIn_{2} $$ S_{4} $ and $ Ag_{2} $$ CO_{3} $, the formed Z-scheme heterostructure can promote the charge separation and photoelectric conversion efficiency. And the concomitant Ag nanoparticles in $ Ag_{2} $$ CO_{3} $ provided multiple functions to enhance the PEC response of the Z-scheme heterostructure. It acts not only as a bridge for the transfer of carriers between $ ZnIn_{2} $$ S_{4} $ and $ Ag_{2} $$ CO_{3} $, promoting the constructed Z-scheme heterostructure, but also as electron mediators to accelerate the transfer of photogenerated carriers and improve the capture of visible light of the Z-scheme heterostructure by surface plasmon resonance (SPR). Compared with single $ Ag_{2} $$ CO_{3} $ and $ ZnIn_{2} $$ S_{4} $, the photocurrent of the designed Z-scheme heterostructure increased more than 20 and 60 times respectively. The fabricated PEC biosensor based on a $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure exhibits sensitive detection to NSE, and presents a linear range of 50 fg·$ mL^{−1} $ ~ 200 ng·$ mL^{−1} $ with a limit of detection of 4.86 fg·$ mL^{−1} $. The proposed PEC biosensor provides a potential approach for clinical diagnosis..
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:415 |
|---|---|
| Enthalten in: |
Analytical & bioanalytical chemistry - 415(2023), 22 vom: 04. Juli, Seite 5551-5562 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Li, Jun [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| BKL: | |
|---|---|
| Themen: |
| RVK: |
|---|
| Anmerkungen: |
© The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
|---|
| doi: |
10.1007/s00216-023-04830-4 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
OLC2145138927 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2145138927 | ||
| 003 | DE-627 | ||
| 005 | 20240118102946.0 | ||
| 007 | tu | ||
| 008 | 240118s2023 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00216-023-04830-4 |2 doi | |
| 035 | |a (DE-627)OLC2145138927 | ||
| 035 | |a (DE-He213)s00216-023-04830-4-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 540 |a 570 |q VZ |
| 082 | 0 | 4 | |a 570 |a 540 |q VZ |
| 084 | |a 12 |2 ssgn | ||
| 084 | |a BIODIV |q DE-30 |2 fid | ||
| 084 | |a VA 4300 |q VZ |2 rvk | ||
| 084 | |a 35.23$jAnalytische Chemie: Allgemeines |2 bkl | ||
| 084 | |a 35.71$jBiochemische Methoden |2 bkl | ||
| 084 | |a 42.03$jMethoden und Techniken der Biologie |2 bkl | ||
| 100 | 1 | |a Li, Jun |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a A $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure-based photoelectrochemical biosensor for neuron-specific enolase |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. | ||
| 520 | |a Abstract An efficient photo-to-electrical signal is pivotal to photoelectrochemical (PEC) biosensors. In our work, a novel PEC biosensor was fabricated for the detection of neuron-specific enolase (NSE) based on a $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure. Due to the overlapping band potentials of the $ ZnIn_{2} $$ S_{4} $ and $ Ag_{2} $$ CO_{3} $, the formed Z-scheme heterostructure can promote the charge separation and photoelectric conversion efficiency. And the concomitant Ag nanoparticles in $ Ag_{2} $$ CO_{3} $ provided multiple functions to enhance the PEC response of the Z-scheme heterostructure. It acts not only as a bridge for the transfer of carriers between $ ZnIn_{2} $$ S_{4} $ and $ Ag_{2} $$ CO_{3} $, promoting the constructed Z-scheme heterostructure, but also as electron mediators to accelerate the transfer of photogenerated carriers and improve the capture of visible light of the Z-scheme heterostructure by surface plasmon resonance (SPR). Compared with single $ Ag_{2} $$ CO_{3} $ and $ ZnIn_{2} $$ S_{4} $, the photocurrent of the designed Z-scheme heterostructure increased more than 20 and 60 times respectively. The fabricated PEC biosensor based on a $ ZnIn_{2} $$ S_{4} $/$ Ag_{2} $$ CO_{3} $ Z-scheme heterostructure exhibits sensitive detection to NSE, and presents a linear range of 50 fg·$ mL^{−1} $ ~ 200 ng·$ mL^{−1} $ with a limit of detection of 4.86 fg·$ mL^{−1} $. The proposed PEC biosensor provides a potential approach for clinical diagnosis. | ||
| 650 | 4 | |a Z-scheme heterostructure | |
| 650 | 4 | |a PEC biosensor | |
| 650 | 4 | |a Ag nanoparticles | |
| 700 | 1 | |a Liu, Shanghua |4 aut | |
| 700 | 1 | |a Dong, Hui |4 aut | |
| 700 | 1 | |a Li, Yueyuan |4 aut | |
| 700 | 1 | |a Liu, Qing |4 aut | |
| 700 | 1 | |a Wang, Shujun |4 aut | |
| 700 | 1 | |a Wang, Ping |4 aut | |
| 700 | 1 | |a Li, Yang |4 aut | |
| 700 | 1 | |a Li, Yueyun |4 aut | |
| 700 | 1 | |a Wei, Qin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Analytical & bioanalytical chemistry |d Springer Berlin Heidelberg, 2002 |g 415(2023), 22 vom: 04. Juli, Seite 5551-5562 |w (DE-627)342328573 |w (DE-600)2071767-2 |w (DE-576)097216798 |x 1618-2642 |7 nnns |
| 773 | 1 | 8 | |g volume:415 |g year:2023 |g number:22 |g day:04 |g month:07 |g pages:5551-5562 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s00216-023-04830-4 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a FID-BIODIV | ||
| 912 | |a SSG-OLC-CHE | ||
| 912 | |a GBV_ILN_267 | ||
| 912 | |a GBV_ILN_2018 | ||
| 912 | |a GBV_ILN_4277 | ||
| 936 | r | v | |a VA 4300 |
| 936 | b | k | |a 35.23$jAnalytische Chemie: Allgemeines |q VZ |0 106417940 |0 (DE-625)106417940 |
| 936 | b | k | |a 35.71$jBiochemische Methoden |q VZ |0 106417398 |0 (DE-625)106417398 |
| 936 | b | k | |a 42.03$jMethoden und Techniken der Biologie |q VZ |0 10641013X |0 (DE-625)10641013X |
| 951 | |a AR | ||
| 952 | |d 415 |j 2023 |e 22 |b 04 |c 07 |h 5551-5562 | ||