Evaluating an under-mattress sleep monitor compared to a peripheral arterial tonometry home sleep apnea test device in the diagnosis of obstructive sleep apnea

Study objectives To evaluate whether or not the apnea–hypopnea index (AHI) from a peripheral arterial tonometry (PAT) home sleep apnea test (HSAT) is equivalent to the AHI provided by the mean of one, three, or seven nights from the Withings Sleep Analyzer (WSA) under-mattress device. Methods We prospectively enrolled patients with suspected OSA in whom a PAT-HSAT was ordered. Eligible patients used the WSA for seven to nine nights. PAT data were scored using the device’s intrinsic machine learning algorithms to arrive at the AHI using both 3% and 4% desaturation criteria for hypopnea estimations (PAT3%-AHI and PAT4%-AHI, respectively). These were then compared with the WSA-estimated AHI (WSA-AHI). Results Of 61 patients enrolled, 35 completed the study with valid PAT and WSA data. Of the 35 completers 16 (46%) had at least moderately severe OSA (PAT3%-AHI ≥ 15). The seven-night mean WSA-AHI was 2.13 (95%CI = − 0.88, 5.14) less than the PAT3%-AHI, but 5.64 (95%CI = 2.54, 8.73) greater than the PAT4%-AHI. The accuracy and area under the receiver operating curve (AUC) using the PAT3%-AHI ≥ 15 were 77% and 0.87 and for PAT4%-AHI ≥ 15 were 77% and 0.85, respectively. The one-, three-, or seven-night WSA-AHI were not equivalent to either the 3% or 4% PAT-AHI (equivalency threshold of ± 2.5 using the two one-sided t-test method). Conclusions The WSA derives estimates of the AHI unobtrusively over many nights, which may prove to be a valuable clinical tool. However, the WSA-AHI over- or underestimates the PAT-AHI in clinical use, and the appropriate use of the WSA in clinical practice will require further evaluation. Trial registration ClinicalTrials.gov Identifier: NCT04778748..

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Sleep and breathing - 27(2022), 4 vom: 28. Nov., Seite 1433-1441

Sprache:

Englisch

Beteiligte Personen:

Jagielski, Jack T. [VerfasserIn]
Bibi, Noor [VerfasserIn]
Gay, Peter C. [VerfasserIn]
Junna, Mithri R. [VerfasserIn]
Carvalho, Diego Z. [VerfasserIn]
Williams, Julie A. [VerfasserIn]
Morgenthaler, Timothy I. [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Algorithms
Diagnostic tests, Routine
Home sleep apnea tests
Mobile applications
Obstructive sleep apnea
Peripheral arterial tonometry

Anmerkungen:

© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s11325-022-02751-7

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2145030034

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