Stem cell therapy for traumatic brachial plexus injury
Abstract Stem cell therapy is rapidly evolving, with preclinical studies showing various stem cell types successfully promoting peripheral nerve regeneration. Despite the lack of clinical studies demonstrating efficacy and safety, the number of commercial entities marketing and promoting this treatment direct to patients is also increasing. We describe three adult traumatic brachial plexus injury (BPI) patients who had stem cell therapies prior to consultation in a multidisciplinary brachial plexus clinic. No functional improvement was noted at long-term follow-up despite claims reported by the commercial entities. Considerations and implications of stem cell application in BPI patients are reviewed..
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:165 |
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Enthalten in: |
Acta neurochirurgica - 165(2023), 8 vom: 30. Juni, Seite 2011-2014 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Lee, Ellen Y. [VerfasserIn] |
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Links: |
Volltext [lizenzpflichtig] |
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Themen: |
Cell therapy |
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RVK: |
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Anmerkungen: |
© The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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doi: |
10.1007/s00701-023-05675-7 |
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funding: |
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PPN (Katalog-ID): |
OLC2144894353 |
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520 | |a Abstract Stem cell therapy is rapidly evolving, with preclinical studies showing various stem cell types successfully promoting peripheral nerve regeneration. Despite the lack of clinical studies demonstrating efficacy and safety, the number of commercial entities marketing and promoting this treatment direct to patients is also increasing. We describe three adult traumatic brachial plexus injury (BPI) patients who had stem cell therapies prior to consultation in a multidisciplinary brachial plexus clinic. No functional improvement was noted at long-term follow-up despite claims reported by the commercial entities. Considerations and implications of stem cell application in BPI patients are reviewed. | ||
650 | 4 | |a Traumatic brachial plexus injury | |
650 | 4 | |a Stem cells | |
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700 | 1 | |a Adeeb, Nimer |4 aut | |
700 | 1 | |a Bishop, Allen T. |4 aut | |
700 | 1 | |a Shin, Alexander Y. |4 aut | |
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