Details der Publikation - Recent Investigation on Synthetic ‘Triazoles’ Scaffold as Potential Pharmacological Agents: A Comprehensive Survey

Recent Investigation on Synthetic ‘Triazoles’ Scaffold as Potential Pharmacological Agents: A Comprehensive Survey

Background Triazoles, a five-membered aromatic ring with three nitrogen atoms can effortlessly bind with a variety of enzymes and receptors in the biological system through non-covalent or covalent interactions and thus showed various biological activities. The research on triazole-based derivatives is a bustling topic and countless successes have been achieved. Enormously, a large number of triazole derivatives as clinical candidates or drugs have been used for the treatment of various diseases which have shown their progress and wide potential as medicinal agents. The diverse role of the triazole ring has evoked the interest of researchers in the development of novel triazole derivatives with promising biological activities. Main Text This review mainly covers various pharmacological activities such as anticancer, antitubercular, antifungal, anti-inflammatory, antimicrobial, anticonvulsant, anti-HIV, antimalarial, etc. Conclusion This review encourages new thoughts in the quest for the rational design of new more potent and less toxic triazole derivatives as medicinal drugs..

Medienart:	E-Artikel

Erscheinungsjahr:	2023
Erschienen:	2023

Enthalten in:	Zur Gesamtaufnahme - volume:6
Enthalten in:	Chemistry Africa - 6(2023), 4 vom: 18. Feb., Seite 1679-1697

Sprache:	Englisch

Beteiligte Personen:	Shah, Bhumi M. [VerfasserIn] Modi, Palmi [VerfasserIn] Trivedi, Priti [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

Themen:	Anti-cancer Anticonvulsant Antifungal Antitubercular Pharmacology drugs Triazoles

Anmerkungen:	© The Tunisian Chemical Society and Springer Nature Switzerland AG 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:	10.1007/s42250-023-00617-3

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2144821909

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Recent Investigation on Synthetic ‘Triazoles’ Scaffold as Potential Pharmacological Agents: A Comprehensive Survey

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