Approaches for in vitro propagation and production of plumbagin in Plumbago spp.

Abstract The genus Plumbago (family Plumbaginaceae), commonly known as leadwort, is a sub-tropical shrub that produces secondary metabolite plumbagin, which is employed by pharmaceutical companies and in clinical research. Plumbagin is a potent pharmaceutical because of its anti-microbial, anti-malarial, antifungal, anti-inflammatory, anti-carcinogenic, anti-fertility, anti-plasmodium, antioxidant, anti-diabetic, and other effects. This review documents the biotechnological innovations used to produce plumbagin. The use of modern biotechnological techniques can lead to a variety of benefits, including better yield, increased extraction efficiency, mass production of plantlets, genetic stability, increased biomass, and more. Large-scale in vitro propagation is necessary to minimize over-exploitation of the natural population and allow the use of various biotechnological techniques to improve the plant species and secondary metabolite production. During in vitro culture, optimum conditions are requisites for explant inoculation and plant regeneration. In this review, we provide information on various aspects of plumbagin, depicting its structure, biosynthesis, and biotechnological aspects (both conventional and advanced) along with the future prospects. Key Points • Critical assessment on in vitro biotechnology in Plumbago species • In vitro propagation of Plumbago and elicitation of plumbagin • Biosynthesis and sustainable production of plumbagin.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:107

Enthalten in:

Applied microbiology and biotechnology - 107(2023), 13 vom: 18. Mai, Seite 4119-4132

Sprache:

Englisch

Beteiligte Personen:

Pandey, Devendra Kumar [VerfasserIn]
Katoch, Kajal [VerfasserIn]
Das, Tuyelee [VerfasserIn]
Majumder, Madhumita [VerfasserIn]
Dhama, Kuldeep [VerfasserIn]
Mane, Abhijit Bhagwan [VerfasserIn]
Gopalakrishnan, Abilash Valsala [VerfasserIn]
Dey, Abhijit [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

58.30$jBiotechnologie

42.30$jMikrobiologie

Themen:

Elicitation
In vitro propagation
Micropropagation
Plumbagin

RVK:

RVK Klassifikation

Anmerkungen:

© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s00253-023-12511-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2144228477

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