Early shoulder-girdle MRI findings in severe COVID-19–related intensive care unit-acquired weakness: a prospective cohort study

Objective To describe clinical and early shoulder-girdle MR imaging findings in severe COVID-19–related intensive care unit-acquired weakness (ICU-AW) after ICU discharge. Methods A single-center prospective cohort study of all consecutive patients with COVID-19–related ICU-AW from November 2020 to June 2021. All patients underwent similar clinical evaluations and shoulder-girdle MRI within the first month and then 3 months (± 1 month) after ICU discharge. Results We included 25 patients (14 males; mean [SD] age 62.4 [12.5]). Within the first month after ICU discharge, all patients showed severe proximal predominant bilateral muscular weakness (mean Medical Research Council total score = 46.5/60 [10.1]) associated with bilateral, peripheral muscular edema-like MRI signals of the shoulder girdle in 23/25 (92%) patients. At 3 months, 21/25 (84%) patients showed complete or quasi-complete resolution of proximal muscular weakness (mean Medical Research Council total score > 48/60) and 23/25 (92%) complete resolution of MRI signals of the shoulder girdle, but 12/20 (60%) patients experienced shoulder pain and/or shoulder dysfunction. Conclusions Early shoulder-girdle MRI findings in COVID-19–related ICU-AW included muscular edema-like peripheral signal intensities, without fatty muscle involution or muscle necrosis, with favorable evolution at 3 months. Precocious MRI can help clinicians distinguish critical illness myopathy from alternative, more severe diagnoses and can be useful in the care of patients discharged from intensive care with ICU-AW. Key Points •We describe the clinical and shoulder-girdle MRI findings of COVID-19–related severe intensive care unit-acquired weakness. •This information can be used by clinicians to achieve a nearly specific diagnosis, distinguish alternative diagnoses, assess functional prognosis, and select the more appropriate health care rehabilitation and shoulder impairment treatment..

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

European radiology - 33(2023), 7 vom: 13. März, Seite 4994-5006

Sprache:

Englisch

Beteiligte Personen:

Daste, Camille [VerfasserIn]
Mihoubi, Fadila [VerfasserIn]
Roren, Alexandra [VerfasserIn]
Dumitrache, Alina [VerfasserIn]
Carlier, Nicolas [VerfasserIn]
Benghanem, Sarah [VerfasserIn]
Ruttimann, Aude [VerfasserIn]
Mira, Jean-Paul [VerfasserIn]
Pène, Frédéric [VerfasserIn]
Roche, Nicolas [VerfasserIn]
Seror, Paul [VerfasserIn]
Nguyen, Christelle [VerfasserIn]
Rannou, François [VerfasserIn]
Drapé, Jean-Luc [VerfasserIn]
Lefèvre-Colau, Marie-Martine [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

COVID-19
Intensive care unit
Magnetic resonance imaging
Muscle weakness
Shoulder

RVK:

RVK Klassifikation

Anmerkungen:

© The Author(s), under exclusive licence to European Society of Radiology 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s00330-023-09468-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2144057524

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