Maternal and Neonatal Outcomes of Pregnancy within 7 years after Roux-Y Gastric Bypass or Sleeve Gastrectomy Surgery

Purpose Few studies examine whether maternal and neonatal outcomes differ by time from metabolic and bariatric surgery (MBS) to conception. We describe maternal and neonatal outcomes among women with pregnancy after Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) overall and by whether conception occurred during the period when pregnancy is not recommended (< 18 months postoperative) versus later. Materials and Methods A prospective cohort study enrolled 135 US adult women (median age, 30 years, body mass index [BMI], 47.2 kg/$ m^{2} $) who underwent RYGB or SG (2006–2009) and subsequently reported ≥ 1 pregnancy within 7 years. Participants self-reported pregnancy-related information annually. Differences in prevalence of maternal and neonatal outcomes by postoperative conception timeframe (< 18 versus ≥ 18 months) were assessed. Results Thirty-one women reported ≥ 2 postoperative pregnancies. At time of postoperative conception (median 26 [IQR:22–52] months postoperative) median BMI was 31 (IQR:27–36) kg/$ m^{2} $. Excessive gestational weight gain (55%), cesarean section (42%) and preterm labor or rupture of membranes (40%) were the most common maternal outcomes. Forty percent of neonates had a composite outcome of still birth (1%), preterm birth (26%), small for gestational age (11%), or neonatal intensive care unit admission (8%). Prevalence of outcomes did not statistically significantly differ by timeframe. Conclusion In US women who conceived ≤ 7 years following RYGB or SG, 40% of neonates had the composite neonatal outcome. The prevalence of maternal and neonatal outcomes post-MBS were not statistically significant by conception timeframe. Graphical Abstract.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

Obesity surgery - 33(2023), 6 vom: 04. Apr., Seite 1764-1772

Sprache:

Englisch

Beteiligte Personen:

White, Gretchen E. [VerfasserIn]
Courcoulas, Anita P. [VerfasserIn]
Broskey, Nicholas T. [VerfasserIn]
Rogan, Sarah C. [VerfasserIn]
Jeyabalan, Arun [VerfasserIn]
King, Wendy C. [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Large for gestational age
Pregnancy
Roux-en-Y gastric bypass
Sleeve gastrectomy
Small for gestational age

Anmerkungen:

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s11695-023-06575-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2143641532