Metabolism of Various Arsenic Compounds upon Ingestion of Brown Algae by Warm-Blooded Organisms (Review)
Literature data on the metabolism in warm-blooded organisms of inorganic and organic arsenic compounds contained in brown algae are summarized. Their final metabolites are shown to be low-toxic compounds of pentavalent arsenic that are excreted from the body during short-term intake of brown algae but accumulate in it during long-term consumption. Intermediate metabolites (including organic forms) contain toxic trivalent arsenic compounds. Acertain amount of toxic trivalent arsenic compounds can be present in the gastrointestinal tract because of the reversible oxidation of trivalent arsenic compounds to pentavalent arsenic compounds. These compounds pose a risk to human health when brown algae are regularly ingested as foods, dietary supplements, and herbal medicines. Regulation of the total arsenic content in medicinal herbal raw materials and medicinal herbal preparations is shown to be preferable to regulation of the content of inorganic arsenic forms..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:57 |
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| Enthalten in: |
Pharmaceutical chemistry journal - 57(2023), 1 vom: Apr., Seite 83-88 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shchukin, V. M. [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
Brown algae |
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| Anmerkungen: |
© Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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| doi: |
10.1007/s11094-023-02854-9 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2134816678 |
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| 520 | |a Literature data on the metabolism in warm-blooded organisms of inorganic and organic arsenic compounds contained in brown algae are summarized. Their final metabolites are shown to be low-toxic compounds of pentavalent arsenic that are excreted from the body during short-term intake of brown algae but accumulate in it during long-term consumption. Intermediate metabolites (including organic forms) contain toxic trivalent arsenic compounds. Acertain amount of toxic trivalent arsenic compounds can be present in the gastrointestinal tract because of the reversible oxidation of trivalent arsenic compounds to pentavalent arsenic compounds. These compounds pose a risk to human health when brown algae are regularly ingested as foods, dietary supplements, and herbal medicines. Regulation of the total arsenic content in medicinal herbal raw materials and medicinal herbal preparations is shown to be preferable to regulation of the content of inorganic arsenic forms. | ||
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| 700 | 1 | |a Bunyatyan, N. O. |4 aut | |
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