Utilizing Fe (III)-doped carbon quantum dots as a nanoprobe for deferiprone determination in exhaled breath condensate

A fluorescence “turn-off” technique was used for the quantification of deferiprone (DEF) in the exhaled breath condensate. Fe (III)-doped carbon dots (CDs) were synthesized with a hydrothermal method as a fluorescent nanoprobe. The prepared Fe (III)-doped CDs selectively and sensitively detect DEF in the concentration range of 0.05–4.0 μg $ mL^{−1} $ using a fluorescence quenching mechanism and with a limit of detection of 0.012 μg $ mL^{−1} $. As DEF acts as a strong iron chelator, the probe has the potential for DEF analysis in the presence of major interfering chemicals. The significant properties of the prepared probe, such as high stability, low cost, quick analysis, and simple operation, make it a helpful tool in bioanalytical chemistry. Graphical Abstract A schematic representation of Fe (III)–doped carbon quantum dots as a nanoprobe for deferiprone analysis.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:77

Enthalten in:

Chemical papers - 77(2022), 3 vom: 07. Nov., Seite 1445-1453

Sprache:

Englisch

Beteiligte Personen:

Sefid-Sefidehkhan, Yasaman [VerfasserIn]
Mokhtari, Mehdi [VerfasserIn]
Jouyban, Abolghasem [VerfasserIn]
Khoubnasabjafari, Maryam [VerfasserIn]
Jouyban-Gharamaleki, Vahid [VerfasserIn]
Rahimpour, Elaheh [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Deferiprone
Exhaled breath condensate
Fe(III)-doped carbon quantum dots
Spectrofluorimetry

Anmerkungen:

© Institute of Chemistry, Slovak Academy of Sciences 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s11696-022-02563-9

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2134163453

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