Epidemiology and characteristics of common forms of anterior uveitis at initial presentation in a tertiary facility in Japan

Purpose To elucidate detailed epidemiological profile of common types of anterior uveitis (AU) in real-world clinical setting of a tertiary facility in Japan, and to evaluate the characteristic clinical findings at initial presentation. Study design Retrospective cohort study. Methods Clinical charts of 275 patients (335 eyes) aged 52.5 ± 19.1 years were reviewed retrospectively. Herpetic AU was diagnosed by multiplex polymerase chain reaction tests using aqueous humor. Time of uveitis onset, gender, laterality, disease course since the initial onset of AU, visual acuity (VA) and intraocular pressure (IOP) at first visit, and definitive diagnosis were collected from clinical charts. Results Acute AU (AAU) was the most common (21.8%) form of AU; followed by herpetic AU (20.7%) comprising Herpes Simplex Virus (HSV) (8.0%), Varicella Zoster Virus (VZV) (9.1%) and cytomegalo virus (CMV) (3.6%); scleritis (13.5%); diabetic iritis (7.6%), and Posner-Schlossman syndrome (5.5%). Unilateral AU constituted 78.2%, and VA less than 20/30 accounted for 31.2%. Of all the eyes, 16.1% had an IOP higher than 20 mmHg, out of which 37.0% had herpetic AU, followed by scleritis in 25.9%, and Posner-Schlossman syndrome (PSS) in 11.1%. AU patients over 60 years of age were 40.4%, in which 34.2% had herpetic AU, followed by scleritis in 14.4% and AAU in 13.5%. Herpetic AU patients were significantly older and had higher IOP compared with AAU patients. Conclusion The most frequent AU was AAU, followed by herpetic AU. Herpetic AU patients were older and had higher intraocular pressure than AAU patients, although VA was equally impaired in both groups..

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:67

Enthalten in:

Japanese journal of ophthalmology - 67(2022), 1 vom: 08. Nov., Seite 22-31

Sprache:

Englisch

Beteiligte Personen:

Okazawa, Rina [VerfasserIn]
Iwai, Seima [VerfasserIn]
Nagura, Koichi [VerfasserIn]
Sora, Daisuke [VerfasserIn]
Sato, Tomohito [VerfasserIn]
Takayama, Kei [VerfasserIn]
Harimoto, Kozo [VerfasserIn]
Kanda, Takayuki [VerfasserIn]
Takeuchi, Masaru [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.95$jAugenheilkunde

Themen:

Acute anterior uveitis
Anterior uveitis
Herpetic anterior uveitis
Uveitis

Anmerkungen:

© Japanese Ophthalmological Society 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s10384-022-00961-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2133553169

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