Mortality in psoriatic arthritis patients, changes over time, and the impact of COVID-19: results from a multicenter Psoriatic Arthritis Registry (PsART-ID)

Background This study aimed to assess the mortality of PsA before and during the COVID-19 pandemic. Methods From the prospective, multicenter PsART-ID (Psoriatic Arthritis Registry-International Database), patients from Turkey were analyzed by linking the registry to the Turkish Cause of Death Registry. The outcome of interest was death from any cause, pre-pandemic (since the onset of registry—March 2014–March 2020), and during the pandemic (March 2020–May 2021). The crude mortality rate and standardized mortality ratio (SMR) were determined. Results There were 1216 PsA patients with a follow-up of 7500 patient-years. Overall, 46 deaths (26 males) were observed. In the pre-pandemic period, SMR for PsA vs the general population was 0.95 (0.61–1.49), being higher in males [1.56 (0.92–2.63)] than females [0.62 (0.33–1.17)]. The crude mortality rate in PsA doubled during the pandemic (pre-pandemic crude mortality rate: 5.07 vs 10.76 during the pandemic) with a higher increase in females (2.9 vs 8.72) than males (9.07 vs 14.73). Conclusion The mortality in PsA was found similar to the general population in the pre-pandemic era. The mortality rates in PsA doubled during the pandemic. Whether PsA patients have more risk of mortality than the general population due to COVID-19 needs further studies. Key Points• Decrease in mortality in PsA might be expected with the more effective treatment options and better disease control.• A crude mortality rate is comparable to the general population and not increased until the pandemic.• Currently, there is a 2-fold increase in crude mortality rate possibly due to the COVID-19..

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:42

Enthalten in:

Clinical rheumatology - 42(2023), 2 vom: 13. Jan., Seite 385-390

Sprache:

Englisch

Beteiligte Personen:

Erden, Abdulsamet [VerfasserIn]
Ayan, Gizem [VerfasserIn]
Kilic, Levent [VerfasserIn]
Solmaz, Dilek [VerfasserIn]
Bakirci, Sibel [VerfasserIn]
Kimyon, Gezmis [VerfasserIn]
Günal, Esen Kasapoglu [VerfasserIn]
Dogru, Atalay [VerfasserIn]
Bayindir, Ozun [VerfasserIn]
Dalkilic, Ediz [VerfasserIn]
Özisler, Cem [VerfasserIn]
Akar, Servet [VerfasserIn]
Cetin, Gözde Yildirim [VerfasserIn]
Tarhan, Emine Figen [VerfasserIn]
Küçüksahin, Orhan [VerfasserIn]
Omma, Ahmet [VerfasserIn]
Gonullu, Emel [VerfasserIn]
Yildiz, Fatih [VerfasserIn]
Ersozlu, Emine Duygu [VerfasserIn]
Cinar, Muhammed [VerfasserIn]
Tufan, Abdurrahman [VerfasserIn]
Pehlevan, Seval [VerfasserIn]
Esmen, Serpil Ergulu [VerfasserIn]
Yilmaz, Sema [VerfasserIn]
Duruoz, Tuncay [VerfasserIn]
Kasifoglu, Timucin [VerfasserIn]
Yazısız, Veli [VerfasserIn]
Aksu, Kenan [VerfasserIn]
Aydin, Sibel Zehra [VerfasserIn]
Kalyoncu, Umut [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.00$jMedizin: Allgemeines

44.83$jRheumatologie$jOrthopädie

Themen:

COVID-19
Mortality
Pandemic
Psoriatic arthritis

Anmerkungen:

© The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

doi:

10.1007/s10067-022-06492-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2133523421

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