Gender-related differences on outcome following transcatheter mitral valve repair (TMVR): a systematic review and meta-analysis

Background The effect of gender on patients with mitral valve regurgitation (MR) undergoing transcatheter mitral valve repair (TMVR) remains to be defined. The aim of the present study is a comprehensive meta-analysis of studies that investigate differences between men and women after TMVR. Methods A systematic literature search was carried out on eight databases to collect all relevant studies on gender-related outcomes of TMVR before March 1, 2021. The main outcomes of interest were mortality, cardiac function, MR class and other complications. Results A total of eight literatures were included, all of which were retrospective observational studies. Compared to women patients, men had lower postoperative New York Heart Association (NYHA) class (OR = 1.53, 95%CI [1.23, 1.91], P = 0.0001) and higher incidence of postoperative acute kidney injury (AKI) (OR = 1.25, 95%CI [1.16, 1.34], P < 0.05). There were no significant difference on mortality in 30 days (OR = 0.95, 95%CI [0.81, 1.11], P = 0.53) and in 2 years (OR = 0.99, 95%CI [0.75, 1.30], P = 0.93), mitral valve regurgitation (MR) class (OR = 1.30, 95%CI [0.97, 1.75], P = 0.08) and incidence of myocardial infarction (MI) (OR = 0.88, 95%CI [0.65, 1.18], P = 0.38), stroke (OR = 0.80, 95%CI [0.63, 1.02], P = 0.08) and bleeding in hospital (OR = 0.84, 95%CI [0.59, 1.19], P = 0.32). Conclusions Our meta-analysis demonstrates that men undergoing TMVR have worse preoperative diseases (diabetes mellitus, coronary artery disease, renal failure and myocardial infarction) while they have superior postoperative NYHA class at one-year. There are no significantly difference in other indexes between men and women..

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Journal of cardiothoracic surgery - 18(2023), 1 vom: 17. Jan.

Sprache:

Englisch

Beteiligte Personen:

Yi, Kang [VerfasserIn]
Gao, Jie [VerfasserIn]
Wang, Wen-Xin [VerfasserIn]
Ma, Yu-Hu [VerfasserIn]
Wang, Wei [VerfasserIn]
He, Shao E. [VerfasserIn]
Xu, Xiao-Min [VerfasserIn]
Li, Peng-Fei [VerfasserIn]
You, Tao [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

Gender differences
Meta-analysis
MitraClip
Mitral valve regurgitation
Systematic reviews
Transcatheter mitral valve repair

Anmerkungen:

© The Author(s) 2023

doi:

10.1186/s13019-023-02123-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2133424229

Zugang & Verfügbarkeit




Zugehörige Publikationen/Bände

    Haven't found what you're looking for?