Outcomes of Children with Unoperated Congenital Heart Disease Admitted to PICU—A Single-Center Experience

Objectives To evaluate the outcomes of children with congenital heart disease (CHD) awaiting surgery admitted to a pediatric intensive care unit (PICU) with acute illness. Methods In this retrospective study from a single center, the outcomes of children up to 18 y of age with unoperated CHD admitted to PICU with acute illness and factors affecting the outcomes, were evaluated. Results Fifty-eight (41 boys) children were included. Median age was 3.2 (1.5, 6) mo. Thirty-six (62%) children had acyanotic CHD (ACHD), and 22 (38%) had cyanotic CHD (CCHD). Most common ACHD was ventricular septal defect (n = 14; 38.8%) and CCHD was double-outlet right ventricle (n = 6; 27.2%). Twenty-four (41%) children underwent surgery - 10 (41.6%) palliative procedure and 14 (58.3%) corrective procedure. Hospital mortality was 50%. Of the operated children, 37.5% died and of the nonoperated children, 58.8% died. Type of the heart disease and surgical intervention was not associated with mortality (p = 0.27 and 0.11). Requirement of vasoactive agents was associated with increased mortality (p = 0.02). In children with ACHD, factors associated with mortality were lower score for weight for age (p = 0.03) and weight for length (p = 0.04), lower admission pH (p = 0.02), hemodynamic instability at admission (p = 0.002), and requirement of vasoactive agents (p = 0.04). Conclusion Children with unoperated CHD with acute illness have high morbidity and mortality. Early diagnosis and surgical interventions in children with CHD are warranted. Trial Registration Trial Registration No. IECPG-571/21.10.2020..

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:89

Enthalten in:

Indian journal of pediatrics - 89(2022), 11 vom: 24. Feb., Seite 1073-1078

Sprache:

Englisch

Beteiligte Personen:

Banothu, Kiran Kumar [VerfasserIn]
Kumar, Arvind [VerfasserIn]
Agarwal, Sheetal [VerfasserIn]
Sankar, Jhuma [VerfasserIn]
Kabra, S. K. [VerfasserIn]
Lodha, Rakesh [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Acute illness
Mortality
Surgical intervention
Unoperated congenital heart disease

Anmerkungen:

© Dr. K C Chaudhuri Foundation 2022

doi:

10.1007/s12098-022-04083-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC213239668X

Zugang & Verfügbarkeit




Zugehörige Publikationen/Bände

    Haven't found what you're looking for?