Association between Preoperative Steroids and Outcomes in Patients Undergoing Pancreaticoduodenectomy using the National Surgical Quality Improvement Program

Background A national study analyzing the association between preoperative steroid use and outcomes after pancreatic resections is lacking. The purpose of this study is to evaluate the association between preoperative steroids and outcomes after pancreaticoduodenectomy using a national database. Materials and Methods A retrospective analysis of patients undergoing pancreaticoduodenectomy was performed using the National Surgical Quality Improvement Program (NSQIP) database (2014–2019). In addition, we utilized propensity score matching to compare patients on preoperative steroids to those who were not. Outcomes measured included 30-day complications and mortality, need for readmission, a prolonged hospital length of stay, delayed gastric emptying, and pancreatic fistula. Results After propensity score matching, there were 438 patients in the steroid group and 876 patients in the no steroid group. There was no difference in pancreatic fistula (23.8% vs. 21.7%; p-0.3), delayed gastric emptying (21.1% vs.20.1%; p-0.06), major complications (31.8% vs. 30.1%; p-0.1), and mortality (3.5% vs. 3.2%; p-0.6) between the two groups. Conclusion Glucocorticoids did not reduce the incidence of overall complications, postoperative fistula, and delayed gastric emptying following pancreaticoduodenectomy..

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:26

Enthalten in:

Journal of gastrointestinal surgery - 26(2022), 6 vom: 09. Feb., Seite 1198-1204

Sprache:

Englisch

Beteiligte Personen:

Aziz, Hassan [VerfasserIn]
Ahmed, Zubair [VerfasserIn]
Abdimajid, Mohamed [VerfasserIn]
Sekigami, Yurie [VerfasserIn]
Hertl, Martin [VerfasserIn]
Goodman, Martin D. [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.87$jGastroenterologie

Themen:

Complications
Glucocorticoids
Pancreatic fistula
Pancreatic surgery

Anmerkungen:

© The Society for Surgery of the Alimentary Tract 2022

doi:

10.1007/s11605-022-05260-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2130846610

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