Frequency and outcomes of gastrointestinal symptoms in patients with Corona Virus Disease-19

Objectives To characterize the frequency and association of gastrointestinal (GI) symptoms with outcomes in patients with corona virus disease 2019 (COVID-19) admitted to the hospital. Methods Records were retrospectively collected from patients admitted to a tertiary care center in Washington, D.C., with confirmed COVID-19 from March 15, 2020 to July 15, 2020. After adjusting for clinical demographics and comorbidities, multivariate logistic regression analysis was performed. Results The most common presenting symptoms of COVID-19 in patients that were admitted to the hospital were cough (38.4%), shortness of breath (37.5%), and fever (34.3%), followed by GI symptoms in 25.9% of patients. The most common GI symptom was diarrhea (12.8%) followed by nausea or vomiting (10.5%), decreased appetite (9.3%), and abdominal pain (3.8%). Patients with diarrhea were more likely to die (odds ratio [OR] 2.750; p = 0.006; confidence interval [CI] 1.329–5.688), be admitted to the intensive care unit (ICU) (OR 2.242; p = 0.019; CI 1.139–4.413), and be intubated (OR 3.155; p = 0.002; CI 1.535–6.487). Additional outcomes analyzed were need for vasopressors, presence of shock, and acute kidney injury. Patients with diarrhea were 2.738 (p = 0.007; CI 1.325–5.658), 2.467 (p = 0.013; CI 1.209–5.035), and 2.694 (p = 0.007; CI 1.305–5.561) times more likely to experience these outcomes, respectively. Conclusions Screening questions should be expanded to include common GI symptoms in patients with COVID-19. Health care providers should note whether their patient is presenting with diarrhea due to the potential implications on disease severity and outcomes..

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:40

Enthalten in:

Indian journal of gastroenterology - 40(2021), 5 vom: 27. Sept., Seite 502-511

Sprache:

Englisch

Beteiligte Personen:

Rogers, Hayley K. [VerfasserIn]
Choi, WonSeok W. [VerfasserIn]
Gowda, Niraj [VerfasserIn]
Nawal, Saadia [VerfasserIn]
Gordon, Brittney [VerfasserIn]
Onyilofor, Chinelo [VerfasserIn]
Rogers, Callie M. [VerfasserIn]
Yamane, David [VerfasserIn]
Borum, Marie L. [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.87$jGastroenterologie

Themen:

Betacoronavirus
COVID-19
Diarrhea
Hospitalized patients
Novel conrona virus
Pandemic
SARS-CoV-2

Anmerkungen:

© Indian Society of Gastroenterology 2021

doi:

10.1007/s12664-021-01191-7

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2129082289

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