Details der Publikation - Potential Role of Zinc in the COVID-19 Disease Process and its Probable Impact on Reproduction

Potential Role of Zinc in the COVID-19 Disease Process and its Probable Impact on Reproduction

Abstract COVID-19 (coronavirus disease 2019) is the current world health crisis, producing extensive morbidity and mortality across all age groups. Given the established roles of zinc in combating oxidative damage and viral infections, zinc is being trialed as a treatment modality against COVID-19. Zinc also has confirmed roles in both male and female reproduction. The possible depletion of zinc with the oxidative events of COVID-19 is especially relevant to the fertility of affected couples. This review aims to present the pathophysiology of COVID-19, especially in relation to reproductive function; the role of zinc in the COVID-19 disease process; and how zinc depletion in concert with cytokine storm and reactive oxygen species production could affect reproduction. It also highlights research areas to better the understanding of COVID-19 and its impact on fertility and potential ways to mitigate the impact..

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:29
Enthalten in:	Reproductive sciences - 29(2021), 1 vom: 07. Jan., Seite 1-6

Sprache:	Englisch

Beteiligte Personen:	Sethuram, Ramya [VerfasserIn] Bai, David [VerfasserIn] Abu-Soud, Husam M. [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

Themen:	Coronavirus Covid-19 Infertility Reactive oxygen species Zinc

Anmerkungen:	© Society for Reproductive Investigation 2021

doi:	10.1007/s43032-020-00400-6

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2128811996

Internformat


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520			\|a Abstract COVID-19 (coronavirus disease 2019) is the current world health crisis, producing extensive morbidity and mortality across all age groups. Given the established roles of zinc in combating oxidative damage and viral infections, zinc is being trialed as a treatment modality against COVID-19. Zinc also has confirmed roles in both male and female reproduction. The possible depletion of zinc with the oxidative events of COVID-19 is especially relevant to the fertility of affected couples. This review aims to present the pathophysiology of COVID-19, especially in relation to reproductive function; the role of zinc in the COVID-19 disease process; and how zinc depletion in concert with cytokine storm and reactive oxygen species production could affect reproduction. It also highlights research areas to better the understanding of COVID-19 and its impact on fertility and potential ways to mitigate the impact.
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Potential Role of Zinc in the COVID-19 Disease Process and its Probable Impact on Reproduction

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