Hemagglutinin-esterase cannot be considered as a candidate for designing drug against COVID-19
We read with interest the article by Patel et al. on the identification of potential inhibitors of coronavirus hemagglutinin-esterase. The authors considered hemagglutinin-esterase as a glycoprotein of SARS-CoV-2 and selected hemagglutinin-esterase as a target to identify potential inhibitors using a combination of various computational approaches, and however, SARS-CoV-2 genome lacks hemagglutinin-esterase gene; thus, hemagglutinin-esterase does not exist in SARS-CoV-2 particle. Graphic abstract.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
|---|---|
| Enthalten in: |
Molecular diversity - 25(2021), 3 vom: 09. Juli, Seite 1999-2000 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zandi, Milad [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| Themen: |
|---|
| Anmerkungen: |
© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 |
|---|
| doi: |
10.1007/s11030-021-10272-w |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
OLC2127058658 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2127058658 | ||
| 003 | DE-627 | ||
| 005 | 20230505123834.0 | ||
| 007 | tu | ||
| 008 | 230505s2021 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s11030-021-10272-w |2 doi | |
| 035 | |a (DE-627)OLC2127058658 | ||
| 035 | |a (DE-He213)s11030-021-10272-w-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 570 |q VZ |
| 100 | 1 | |a Zandi, Milad |e verfasserin |0 (orcid)0000-0002-2145-0196 |4 aut | |
| 245 | 1 | 0 | |a Hemagglutinin-esterase cannot be considered as a candidate for designing drug against COVID-19 |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 | ||
| 520 | |a We read with interest the article by Patel et al. on the identification of potential inhibitors of coronavirus hemagglutinin-esterase. The authors considered hemagglutinin-esterase as a glycoprotein of SARS-CoV-2 and selected hemagglutinin-esterase as a target to identify potential inhibitors using a combination of various computational approaches, and however, SARS-CoV-2 genome lacks hemagglutinin-esterase gene; thus, hemagglutinin-esterase does not exist in SARS-CoV-2 particle. Graphic abstract | ||
| 650 | 4 | |a Hemagglutinin-esterase | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a Genome | |
| 650 | 4 | |a Betacoronavirus | |
| 700 | 1 | |a Soltani, Saber |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Molecular diversity |d Springer International Publishing, 1995 |g 25(2021), 3 vom: 09. Juli, Seite 1999-2000 |w (DE-627)225977672 |w (DE-600)1376507-3 |w (DE-576)9225977670 |x 1381-1991 |7 nnns |
| 773 | 1 | 8 | |g volume:25 |g year:2021 |g number:3 |g day:09 |g month:07 |g pages:1999-2000 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s11030-021-10272-w |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 951 | |a AR | ||
| 952 | |d 25 |j 2021 |e 3 |b 09 |c 07 |h 1999-2000 | ||