Details der Publikation - 1D/2D Co(II) coordination polymers: magnetic properties and application values on the ischemic myocardial infarction by regulating the JAK signaling pathway

1D/2D Co(II) coordination polymers: magnetic properties and application values on the ischemic myocardial infarction by regulating the JAK signaling pathway

Abstract In this present research, two coordination polymers (CPs) containing Co(II) with solvent induced structural diversity are created by the reaction between 5-tert-butylbenzene-1,3-dicarboxylic acid (5-tert-$ H_{2} $IPA) and Co($ NO_{3} $)2·$ 6H_{2} $O in the existence of a nitrogen-donor co-ligand N,N′-bis(3-pyridyl)terephthalamide (L), and for the as-synthesized CPs, their chemical formulae are {[Co(L)1.5(5-tert-IPA)($ H_{2} $O)2]·2.$ 5H_{2} $O}n (1) and {[Co(L)(5-tert-IPA)($ CH_{3} $OH)]·$ 2CH_{3} $OH}n (2). The magnetic performances of two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions. Their assessment of treatment effect on the ischemic myocardial infarction was conducted, and the specific mechanism was explored. Firstly, the enzyme linked immunosorbent assay (ELISA) detection kit was employed and the inflammatory cytokines levels released into plasma was determined. Furthermore, the activation for the JAK/STAT signaling pathway was detected employing real time reverse transcription-polymerase chain reaction (RT-PCR) assay..

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:28
Enthalten in:	Journal of polymer research - 28(2021), 8 vom: 10. Juli

Sprache:	Englisch

Beteiligte Personen:	Han, Xia [VerfasserIn] Jiang, Hong-Lei [VerfasserIn] Yang, Shu-Jing [VerfasserIn] Liu, Wen-Ting [VerfasserIn] Niu, Jiamin [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

BKL:	35.00$jChemie: Allgemeines
Themen:	Coordination polymers Ischemic myocardial infarction Magnetic studies

Anmerkungen:	© The Polymer Society, Taipei 2021

doi:	10.1007/s10965-021-02649-0

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2126562824

Internformat


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520			\|a Abstract In this present research, two coordination polymers (CPs) containing Co(II) with solvent induced structural diversity are created by the reaction between 5-tert-butylbenzene-1,3-dicarboxylic acid (5-tert-$ H_{2} $IPA) and Co($ NO_{3} $)2·$ 6H_{2} $O in the existence of a nitrogen-donor co-ligand N,N′-bis(3-pyridyl)terephthalamide (L), and for the as-synthesized CPs, their chemical formulae are {[Co(L)1.5(5-tert-IPA)($ H_{2} $O)2]·2.$ 5H_{2} $O}n (1) and {[Co(L)(5-tert-IPA)($ CH_{3} $OH)]·$ 2CH_{3} $OH}n (2). The magnetic performances of two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions. Their assessment of treatment effect on the ischemic myocardial infarction was conducted, and the specific mechanism was explored. Firstly, the enzyme linked immunosorbent assay (ELISA) detection kit was employed and the inflammatory cytokines levels released into plasma was determined. Furthermore, the activation for the JAK/STAT signaling pathway was detected employing real time reverse transcription-polymerase chain reaction (RT-PCR) assay.
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1D/2D Co(II) coordination polymers: magnetic properties and application values on the ischemic myocardial infarction by regulating the JAK signaling pathway

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