Clinical manifestations of COVID-19 in the general population: systematic review

Summary Clinical manifestations of COVID-19 are varied in the general population. This study aimed to systematize the literature regarding clinical manifestations of patients with confirmed COVID-19. A systematic review of the literature was conducted. A total of 8070 scientific productions were found in the databases. Among the studies, 184 met the initial inclusion criteria, with a total of 114,046 patients. After complete reading, 32 studies that did not report clinical manifestations were excluded. The 152 publications finally included a total of 41,409 individuals from at least 23 countries and 26 different clinical manifestations were reported. In percentage terms, 6 symptoms had a general prevalence greater than or equal to 25%, namely, fever (58.66%), cough (54.52%), dyspnea (30.82%), malaise (29.75%), fatigue (28.16%) and sputum/secretion (25.33%). Neurological symptoms (20.82%), dermatological manifestations (20.45%), anorexia (20.26%), myalgia (16.9%), sneezing (14.71%), sore throat (14.41%), rhinitis (14.29%), goosebumps (13.49%), headache (12.17%), chest pain (11.49%) and diarrhea (9.59%) were other common symptoms. Only one study reported dermatological manifestations. The least frequent sign/symptom was hemoptysis (1.65%). In studies with more than 100 patients, the 3 main symptoms were fever (57.93%), cough (54.21%), and dyspnea (30.64%). Dermatological manifestations do not appear among the main symptoms. The identification of all clinical manifestations of COVID-19 is essential for an early diagnosis and the adoption of preventive measures..

Medienart:

Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:133

Enthalten in:

Wiener klinische Wochenschrift - 133(2020), 7-8 vom: 26. Nov., Seite 377-382

Sprache:

Englisch

Beteiligte Personen:

da Rosa Mesquita, Rodrigo [VerfasserIn]
Francelino Silva Junior, Luiz Carlos [VerfasserIn]
Santos Santana, Fernanda Mayara [VerfasserIn]
Farias de Oliveira, Tatiana [VerfasserIn]
Campos Alcântara, Rafaela [VerfasserIn]
Monteiro Arnozo, Gabriel [VerfasserIn]
Rodrigues da Silva Filho, Etvaldo [VerfasserIn]
Galdino dos Santos, Aisla Graciele [VerfasserIn]
Oliveira da Cunha, Euclides José [VerfasserIn]
Salgueiro de Aquino, Saulo Henrique [VerfasserIn]
Freire de Souza, Carlos Dornels [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Coronavirus infection
Epidemiology
General symptoms
SARS virus

Anmerkungen:

© Springer-Verlag GmbH Austria, part of Springer Nature 2020

doi:

10.1007/s00508-020-01760-4

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2125061066