Psychotropic Drug-Induced Glaucoma: A Practical Guide to Diagnosis and Management

Abstract This article provides a practical review of the diagnosis and management of angle closure induced by psychotropic agents, including tricyclic antidepressants, antipsychotics and anticonvulsants. Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, monoamine oxidase inhibitors and antipsychotics may trigger angle closure by influencing pupil configuration through adrenergic, anticholinergic, serotonergic or dopaminergic mechanisms. Patients with narrow iridocorneal angles are at risk, and these are more common in people with hypermetropia (near-sightedness), older people and individuals with an Asian background. These patients may benefit from a laser peripheral iridotomy, either prophylactically or to relieve an acute angle-closure episode. An idiosyncratic reaction to medications such as topiramate may lead to angle closure through an alternate mechanism, leading to a uveal effusion. Ophthalmological review may be considered prior to commencing medications in high-risk patients..

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

CNS drugs - 35(2021), 3 vom: 19. Feb., Seite 283-289

Sprache:

Englisch

Beteiligte Personen:

Jain, Neeranjali S. [VerfasserIn]
Ruan, Claire W. [VerfasserIn]
Dhanji, Shanil R. [VerfasserIn]
Symes, Richard J. [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.40$jPharmazie$jPharmazeutika

Anmerkungen:

© The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature 2021

doi:

10.1007/s40263-020-00790-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC212465232X

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