COVID-19 coagulopathy: is it disseminated intravascular coagulation?
Abstract One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
Internal and emergency medicine - 16(2020), 2 vom: 24. Dez., Seite 309-312 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Levi, Marcel [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
-dimer |
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| Anmerkungen: |
© The Author(s) 2020 |
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| doi: |
10.1007/s11739-020-02601-y |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2124313207 |
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| 520 | |a Abstract One of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria. | ||
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a Coagulation | |
| 650 | 4 | |a Thrombosis | |
| 650 | 4 | |a Pulmonary embolism | |
| 650 | 4 | |a -dimer | |
| 650 | 4 | |a Disseminated intravascular coagulation | |
| 650 | 4 | |a Thrombotic microangiopathy | |
| 700 | 1 | |a Iba, Toshiaki |4 aut | |
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