Measurement of upper airway resistances: A simple way to assess its collapsibility?
Purpose The collapsibility of the upper airway is a key factor in the pathogenesis of obstructive sleep apnea (OSA). The exact measurement of this parameter, typically performed by obtaining the critical pressure (Pcrit), has not been introduced into clinical practice. The techniques that are used to measure the upper airway resistance could provide information on its the collapsibility of the airway. The aim of this study was to associate resistance in the upper airway with the presence of OSA. Methods Using a cross-sectional design with a control group, consecutive cases that were seen in the Chest Diseases Sleep Unit were recruited after undergoing nocturnal polysomnography. The upper airway collapsibility was determined based on the change in its resistance from the standing position to the supine position with a flow interruption (Rint) device by measuring the angle formed between the pressure/flow lines (PF angle) between the two positions. Results The PF angle was greater in the OSA group than in the controls: 7.5° (4) vs. 4° (2) (P < .001), with a positive correlation between the width of the angle and the apnea-hypopnea index (AHI) (r: 0.28, P = .03). Placing the threshold level at 10°, a sensitivity of 25% was obtained, along with a specificity of 96%, for the diagnosis of OSA. Conclusion The measurement of resistance in the upper airway using flow interruption (Rint) can predict the presence of moderate and severe OSA with high specificity but low sensitivity..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
Sleep and breathing - 24(2020), 4 vom: 07. Feb., Seite 1531-1535 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cuadrado, Gemma Rubinos [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| BKL: | |
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| Themen: |
Obstructive sleep apnea |
| Anmerkungen: |
© Springer Nature Switzerland AG 2020 |
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| doi: |
10.1007/s11325-020-02026-z |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2121380817 |
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| 245 | 1 | 0 | |a Measurement of upper airway resistances: A simple way to assess its collapsibility? |
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| 520 | |a Purpose The collapsibility of the upper airway is a key factor in the pathogenesis of obstructive sleep apnea (OSA). The exact measurement of this parameter, typically performed by obtaining the critical pressure (Pcrit), has not been introduced into clinical practice. The techniques that are used to measure the upper airway resistance could provide information on its the collapsibility of the airway. The aim of this study was to associate resistance in the upper airway with the presence of OSA. Methods Using a cross-sectional design with a control group, consecutive cases that were seen in the Chest Diseases Sleep Unit were recruited after undergoing nocturnal polysomnography. The upper airway collapsibility was determined based on the change in its resistance from the standing position to the supine position with a flow interruption (Rint) device by measuring the angle formed between the pressure/flow lines (PF angle) between the two positions. Results The PF angle was greater in the OSA group than in the controls: 7.5° (4) vs. 4° (2) (P < .001), with a positive correlation between the width of the angle and the apnea-hypopnea index (AHI) (r: 0.28, P = .03). Placing the threshold level at 10°, a sensitivity of 25% was obtained, along with a specificity of 96%, for the diagnosis of OSA. Conclusion The measurement of resistance in the upper airway using flow interruption (Rint) can predict the presence of moderate and severe OSA with high specificity but low sensitivity. | ||
| 650 | 4 | |a Obstructive sleep apnea | |
| 650 | 4 | |a Obstructive sleep apnea screening | |
| 650 | 4 | |a Upper airway resistance | |
| 650 | 4 | |a Upper airway collapsibility | |
| 700 | 1 | |a Álvarez, Ramón Fernández |4 aut | |
| 700 | 1 | |a Huertas, Julia Herrero |4 aut | |
| 700 | 1 | |a Lopez, Maria Jose Vazquez |4 aut | |
| 700 | 1 | |a Urrutia, Marta Iscar |4 aut | |
| 700 | 1 | |a Clara, Pere Casan |4 aut | |
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