COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients
Introduction Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. Methods Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome. Results Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir. Conclusions This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:48 |
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| Enthalten in: |
Infection - 48(2020), 5 vom: 11. Mai, Seite 681-686 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Härter, Georg [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
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| Anmerkungen: |
© Springer-Verlag GmbH Germany, part of Springer Nature 2020 |
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| doi: |
10.1007/s15010-020-01438-z |
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| PPN (Katalog-ID): |
OLC2119655855 |
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| 520 | |a Introduction Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. Methods Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome. Results Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir. Conclusions This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART. | ||
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| 700 | 1 | |a Roider, Julia |4 aut | |
| 700 | 1 | |a Bickel, Markus |4 aut | |
| 700 | 1 | |a Krznaric, Ivanka |4 aut | |
| 700 | 1 | |a Grunwald, Stephan |4 aut | |
| 700 | 1 | |a Schabaz, Farhad |4 aut | |
| 700 | 1 | |a Gillor, Daniel |4 aut | |
| 700 | 1 | |a Postel, Nils |4 aut | |
| 700 | 1 | |a Mueller, Matthias C. |4 aut | |
| 700 | 1 | |a Müller, Markus |4 aut | |
| 700 | 1 | |a Römer, Katja |4 aut | |
| 700 | 1 | |a Schewe, Knud |4 aut | |
| 700 | 1 | |a Hoffmann, Christian |4 aut | |
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