Details der Publikation - Methemoglobinemia in the Operating Room and Intensive Care Unit: Early Recognition, Pathophysiology, and Management

Methemoglobinemia in the Operating Room and Intensive Care Unit: Early Recognition, Pathophysiology, and Management

Abstract The objectives of this review are to describe the acquired and hereditary causes of methemoglobinemia, to recommend the most sensitive diagnostic tests, and to enable critical care clinicians to rapidly detect and treat methemoglobinemia. To meet these objectives, Internet search engines were queried with the keywords to select articles for review that included case reports, case series, observational, longitudinal, and surveillance studies. The most common causes of methemoglobinemia include oxidizing reactions to cocaine-derived anesthetics, such as benzocaine and lidocaine, to antibiotics, such as dapsone and other sulfonamides, and to gases, such as nitric oxide. Additionally, CO-oximetry is superior to standard pulse oximetry in detecting methemoglobinemia. Finally, effective treatments for methemoglobinemia include intravenous administration of methylene blue, ascorbic acid, and riboflavin. In this manuscript we will discuss methemoglobinemia, how it occurs, and how to treat it..

Medienart:	E-Artikel

Erscheinungsjahr:	2020
Erschienen:	2020

Enthalten in:	Zur Gesamtaufnahme - volume:37
Enthalten in:	Advances in therapy - 37(2020), 5 vom: 19. März, Seite 1714-1723

Sprache:	Englisch

Beteiligte Personen:	Cefalu, John N. [VerfasserIn] Joshi, Tejas V. [VerfasserIn] Spalitta, Matthew J. [VerfasserIn] Kadi, Carson J. [VerfasserIn] Diaz, James H. [VerfasserIn] Eskander, Jonathan P. [VerfasserIn] Cornett, Elyse M. [VerfasserIn] Kaye, Alan D. [VerfasserIn]

Links:	Volltext [kostenfrei]

Themen:	Ascorbic acid Benzocaine Dapsone Hyperbaric oxygen Lidocaine Methemoglobinemia Methylene blue Nitric oxide Pain Riboflavin

Anmerkungen:	© The Author(s) 2020

doi:	10.1007/s12325-020-01282-5

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2117534171

Internformat


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520			\|a Abstract The objectives of this review are to describe the acquired and hereditary causes of methemoglobinemia, to recommend the most sensitive diagnostic tests, and to enable critical care clinicians to rapidly detect and treat methemoglobinemia. To meet these objectives, Internet search engines were queried with the keywords to select articles for review that included case reports, case series, observational, longitudinal, and surveillance studies. The most common causes of methemoglobinemia include oxidizing reactions to cocaine-derived anesthetics, such as benzocaine and lidocaine, to antibiotics, such as dapsone and other sulfonamides, and to gases, such as nitric oxide. Additionally, CO-oximetry is superior to standard pulse oximetry in detecting methemoglobinemia. Finally, effective treatments for methemoglobinemia include intravenous administration of methylene blue, ascorbic acid, and riboflavin. In this manuscript we will discuss methemoglobinemia, how it occurs, and how to treat it.
650		4	\|a Ascorbic acid
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700	1		\|a Kaye, Alan D. \|4 aut
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Methemoglobinemia in the Operating Room and Intensive Care Unit: Early Recognition, Pathophysiology, and Management

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