Details der Publikation - Impact of health care–associated community-onset cellulitis in Korea: a multicenter study

Impact of health care–associated community-onset cellulitis in Korea: a multicenter study

Abstract We conducted a multicenter study to determine the clinical and microbiological characteristics of health care–associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality..

Medienart:	E-Artikel

Erscheinungsjahr:	2019
Erschienen:	2019

Enthalten in:	Zur Gesamtaufnahme - volume:38
Enthalten in:	European journal of clinical microbiology & infectious diseases - 38(2019), 3 vom: 24. Jan., Seite 545-552

Sprache:	Englisch

Beteiligte Personen:	Park, Seong Yeon [VerfasserIn] Kim, Tark [VerfasserIn] Choi, Seong-Ho [VerfasserIn] Jung, Jiwon [VerfasserIn] Yu, Shi Nae [VerfasserIn] Hong, Hyo-Lim [VerfasserIn] Kim, Yong Kyun [VerfasserIn] Park, Se Yoon [VerfasserIn] Song, Eun Hee [VerfasserIn] Park, Ki-Ho [VerfasserIn] Cho, Oh-Hyun [VerfasserIn] Choi, Sang Ho [VerfasserIn] Kwak, Yee Gyung [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

Themen:	Cellulitis Health care–associated infection

RVK:	RVK Klassifikation ELIB24 ELIB09

Anmerkungen:	© Springer-Verlag GmbH Germany, part of Springer Nature 2019

doi:	10.1007/s10096-018-03456-0

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2109401737

Internformat


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520			\|a Abstract We conducted a multicenter study to determine the clinical and microbiological characteristics of health care–associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality.
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Impact of health care–associated community-onset cellulitis in Korea: a multicenter study

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