Details der Publikation - Fast recovery with etanercept in patients affected by polymyalgia rheumatica and decompensated diabetes: a case-series study

Fast recovery with etanercept in patients affected by polymyalgia rheumatica and decompensated diabetes: a case-series study

Abstract We enrolled nine consecutive patients affected by newly diagnosed polymyalgia rheumatica and decompensated diabetes mellitus. All patients were treated with etanercept (25 mg twice weekly) and prednisone and were followed up to 1 year. At the sixth-month follow-up, etanercept and prednisone were withdrawn. Patients were seen at regular intervals (days 0, 30, 60, 90, 150, 180) and the following variables determined: erythrocytes sedimentation rate, C-reactive protein, fasting serum glucose, pain measured by visual analog scale, and the Health Assessment Questionnaire. Our results indicate that etanercept might have some steroid-sparing effects, but controlled investigations are needed to support etanercept use in clinical practice for this kind of patients..

Medienart:	E-Artikel

Erscheinungsjahr:	2008
Erschienen:	2008

Enthalten in:	Zur Gesamtaufnahme - volume:28
Enthalten in:	Clinical rheumatology - 28(2008), 1 vom: 23. Okt.

Sprache:	Englisch

Beteiligte Personen:	Corrao, Salvatore [VerfasserIn] Pistone, Giovanni [VerfasserIn] Scaglione, Rosario [VerfasserIn] Colomba, Daniela [VerfasserIn] Calvo, Luigi [VerfasserIn] Licata, Giuseppe [VerfasserIn]

Links:	Volltext [lizenzpflichtig]

BKL:	44.00$jMedizin: Allgemeines 44.83$jRheumatologie$jOrthopädie
Themen:	Biological therapy Decompensated diabetes mellitus Etanercept Polymyalgia rheumatica Steroid therapy

Anmerkungen:	© Clinical Rheumatology 2008

doi:	10.1007/s10067-008-1026-6

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC2109217022

Internformat


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520			\|a Abstract We enrolled nine consecutive patients affected by newly diagnosed polymyalgia rheumatica and decompensated diabetes mellitus. All patients were treated with etanercept (25 mg twice weekly) and prednisone and were followed up to 1 year. At the sixth-month follow-up, etanercept and prednisone were withdrawn. Patients were seen at regular intervals (days 0, 30, 60, 90, 150, 180) and the following variables determined: erythrocytes sedimentation rate, C-reactive protein, fasting serum glucose, pain measured by visual analog scale, and the Health Assessment Questionnaire. Our results indicate that etanercept might have some steroid-sparing effects, but controlled investigations are needed to support etanercept use in clinical practice for this kind of patients.
650		4	\|a Biological therapy
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700	1		\|a Pistone, Giovanni \|4 aut
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700	1		\|a Licata, Giuseppe \|4 aut
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Fast recovery with etanercept in patients affected by polymyalgia rheumatica and decompensated diabetes: a case-series study

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