Successful perioperative infection control measures after gastroenterological surgery reduced the number of cases of methicillin-resistant Staphylococcus aureus or Clostridioides (Clostridium) difficile infection to almost zero over a 30-year period: a single-department experience

Purpose To investigate changes in the incidence of postoperative infections in the surgical department of a teaching hospital. Methods During the 30-year period from September 1987 to August 2017, 11,568 gastroenterological surgical procedures were performed in our surgical department. This 30-year period was divided into seven periods (A–G), ranging from 2 to 7 years each and based on the infection control methods used in each period. We then compared the rates of incisional surgical site infection (SSI) and organ/space SSI; remote infection (RI) including respiratory tract infection (RTI), intravascular catheter-related infection, and urinary tract infection (UTI); and antibiotic-associated colitis caused by methicillin-resistant Staphylococcus aureus (MRSA) enteritis or Clostridioides (Clostridium) difficile-associated disease (CDAD) among the seven periods. Results In periods B (September 1990–August 1997) and E (November 2004–July 2007), when a unique antibiotic therapy devised in our department was in use, MRSA was isolated from only 0.3% and 0.4% of surgical patients, respectively, and these rates were significantly lower than those in the other periods (p < 0.05). The rate of CDAD increased during period F (August 2007–July 2014), but in period G (August 2014–August 2017), restrictions were placed on the use of antibiotics with a strong anti-anaerobic action and, in this period, the rate of CDAD was only 0.04%, which was significantly lower than that in period F (p < 0.05). Conclusions Limiting the use of antibiotics that tend to disrupt the intestinal flora may reduce the rates of MRSA infection and CDAD after gastroenterological surgery..

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Surgery today - 50(2019), 3 vom: 23. Okt., Seite 258-266

Sprache:

Englisch

Beteiligte Personen:

Kusachi, Shinya [VerfasserIn]
Watanabe, Manabu [VerfasserIn]
Asai, Koji [VerfasserIn]
Kiribayashi, Takaharu [VerfasserIn]
Niitsuma, Toru [VerfasserIn]
Nishimuta, Hironobu [VerfasserIn]
Saida, Yoshihisa [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.65$jChirurgie

Themen:

MRSA
Post-operative infection
SSI
Tazobactam/piperacillin

RVK:

RVK Klassifikation

Anmerkungen:

© Springer Nature Singapore Pte Ltd. 2019

doi:

10.1007/s00595-019-01899-2

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2107583153

Zugang & Verfügbarkeit




Zugehörige Publikationen/Bände

    Haven't found what you're looking for?