High-pitch dual-source CT coronary angiography with low volumes of contrast medium

Objectives To assess the effect of lower volumes of contrast medium (CM) on image quality in high-pitch dual-source computed tomography coronary angiography (CTCA). Methods One-hundred consecutive patients (body weight 65–85 kg, stable heart rate ≤65 bpm, cardiac index ≥2.5 L/min/$ m^{2} $) referred for CTCA were prospectively enrolled. Patients were randomly assigned to one of five groups of different CM volumes ($ G_{30} $, 30 mL; $ G_{40} $, 40 mL; $ G_{50} $, 50 mL; $ G_{60} $, 60 mL; $ G_{70} $, 70 mL; flow rate 5 mL/s each, iodine content 370 mg/mL). Attenuation within the proximal and distal coronary artery segments was analysed. Results Mean attenuation for men and women ranged from 345.0 and 399.1 HU in $ G_{30} $ to 478.2 and 571.8 HU in $ G_{70} $. Mean attenuation values were higher in groups with higher CM volumes (P < 0.0001) and higher in women than in men (P < 0.0001). The proportions of segments with attenuation of at least 300 HU in $ G_{30} $, $ G_{40} $, $ G_{50} $, $ G_{60} $ and $ G_{70} $ were 89 %, 95 %, 98 %, 98 % and 99 %. CM volume of 30 mL in women and 40 mL in men proved to be sufficient to guarantee attenuation of at least 300 HU. Conclusions In selected patients high-pitch dual-source CTCA can be performed with CM volumes of 40 mL in men or 30 mL in women. Key Points • High-pitch dual-source coronary angiography is feasible with low contrast media volumes. • Traditional injection rules still apply: higher volumes result in higher enhancement. • The patient’s gender is a co-factor determining the level of contrast enhancement. • Volumes can be reduced down to 30–40 mL in selected patients..

Medienart:

E-Artikel

Erscheinungsjahr:

2013

Erschienen:

2013

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

European radiology - 24(2013), 1 vom: 15. Aug., Seite 120-127

Sprache:

Englisch

Beteiligte Personen:

Lembcke, Alexander [VerfasserIn]
Schwenke, Carsten [VerfasserIn]
Hein, Patrick A. [VerfasserIn]
Knobloch, Gesine [VerfasserIn]
Durmus, Tahir [VerfasserIn]
Hamm, Bernd [VerfasserIn]
Huppertz, Alexander [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

Themen:

Cardiac-gated imaging techniques
Contrast media
Coronary angiography
Coronary artery disease
Multidetector computed tomography

RVK:

RVK Klassifikation

Anmerkungen:

© European Society of Radiology 2013

doi:

10.1007/s00330-013-2988-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2092266888

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