Pulmonary embolism and portal vein thrombosis in an immunocompetent adolescent with acute cytomegalovirus hepatitis

Abstract Cytomegalovirus infection is usually asymptomatic or resembles infectious mononucleosis with fever, pharyngitis, arthralgias, lymphadenopathy, and atypical lymphocytosis. Even though primary CMV infection is usually self-limited in healthy individuals, significant complications can develop in immunocompromised patients. Venous or arterial thromboembolic phenomena are uncommon, yet very serious complications of CMV infection. Most published reports describe immunosupressed patients after organ transplantation or in the presence of HIV co-infection. However, thrombotic events in CMV infected immunocompetent individuals may occur. We describe the case of an immunocompetent adolescent with acute cytomegalovirus hepatitis that was complicated with pulmonary embolism and portal vein thrombosis. To our knowledge, this is the first reported case in which these two thrombotic phenomena occurred simultaneously in an adolescent with no obvious predisposing factors for thrombosis in the setting of an acute CMV infection..

Medienart:

E-Artikel

Erscheinungsjahr:

2008

Erschienen:

2008

Enthalten in:

Zur Gesamtaufnahme - volume:28

Enthalten in:

Journal of thrombosis and thrombolysis - 28(2008), 4 vom: 31. Dez.

Sprache:

Englisch

Beteiligte Personen:

Ladd, Antonio Mendoza [VerfasserIn]
Goyal, Rakesh [VerfasserIn]
Rosainz, Louis [VerfasserIn]
Baiocco, Peter [VerfasserIn]
DiFabrizio, Larry [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

44.85$jKardiologie$jAngiologie

Themen:

Cytomegalovirus hepatitis
Hypercoagulability
Portal vein thrombosis
Pulmonary emboli

Anmerkungen:

© Springer Science+Business Media, LLC 2008

doi:

10.1007/s11239-008-0303-1

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2083917820