Interaction of Antioxidant Trace Minerals Affecting Blood Picture Including Antioxidant Profile of Healthy Buffalo (Bubalus bubalis) Calves
Abstract Copper (Cu) and selenium (Se) are antioxidants and essential trace elements that have mutual interaction and are reported to have beneficial effects at supranutritional levels. The experiment was executed to evaluate the individual impact of supranutritional levels of targeted elements with the effect of their interactions in buffalo calves. Twenty male Murrah buffalo calves of about 8–9 months (bodyweight 112.1 ± 7.69 kg) were distributed into four groups of five calves in each group and fed either a control (C) diet or supplemented with supranutritional levels of Cu ($ T_{1} $), Se ($ T_{2} $), or combination of both ($ T_{3} $) for 120 days. Higher (P = 0.015) values of packed cell volume were observed in group $ T_{2} $ at day 120; otherwise, all other hematological parameters remained comparable among groups. Over the period (day 120 vs. day 0), an enhancement in the percentage of lymphocytes (P = 0.006) with a reduction in neutrophils (P = 0.028) and hemoglobin (P = 0.024) values was observed in the control group. An enhancement in the percentage of monocytes (P = 0.031), with a reduced percentage of neutrophils (P = 0.022), was reported in groups $ T_{2} $ and $ T_{3} $, respectively. Interaction of Cu and Se at supranutritional level (T3) dramatically reduced plasma Cu (P = 0.008) level against the control values, with an improvement in Se markers (i.e., plasma Se, P = 0.041 and enzyme glutathione peroxidase, P = 0.057) over the values in calves fed supplemental Se alone ($ T_{2} $). Additionally, Cu ($ T_{1} $ and $ T_{3} $) was forced to decline (P < 0.05) Zn level in the plasma of buffalo calves. Cu ($ T_{1} $, P < 0.05) and Se ($ T_{2} $ and $ T_{3} $, P ≤ 0.01) supplementation was able to improve their respective plasma levels. The interaction of two trace elements at the supranutritional level further helped in reducing the lipid peroxidation (P = 0.01) values as well. Though antioxidant vitamins and cell-mediated immunity remained unaffected, humoral immunity against antigen P. multocida was high (P = 0.005) in the group $ T_{2} $. The conclusion may be drawn that supranutritional Cu and Se were capable to influence certain blood parameters with an additional interaction effect due to simultaneous supplementation in buffalo calves..
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:201 |
|---|---|
| Enthalten in: |
Biological trace element research - 201(2022), 1 vom: 29. Jan., Seite 156-169 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Mudgal, Vishal [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| Themen: |
Antioxidant profile |
|---|
| Anmerkungen: |
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 |
|---|
| doi: |
10.1007/s12011-022-03122-9 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
OLC2080254529 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2080254529 | ||
| 003 | DE-627 | ||
| 005 | 20230510122625.0 | ||
| 007 | tu | ||
| 008 | 230131s2022 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s12011-022-03122-9 |2 doi | |
| 035 | |a (DE-627)OLC2080254529 | ||
| 035 | |a (DE-He213)s12011-022-03122-9-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 570 |q VZ |
| 084 | |a 12 |2 ssgn | ||
| 084 | |a BIODIV |q DE-30 |2 fid | ||
| 100 | 1 | |a Mudgal, Vishal |e verfasserin |0 (orcid)0000-0002-6907-736X |4 aut | |
| 245 | 1 | 0 | |a Interaction of Antioxidant Trace Minerals Affecting Blood Picture Including Antioxidant Profile of Healthy Buffalo (Bubalus bubalis) Calves |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 | ||
| 520 | |a Abstract Copper (Cu) and selenium (Se) are antioxidants and essential trace elements that have mutual interaction and are reported to have beneficial effects at supranutritional levels. The experiment was executed to evaluate the individual impact of supranutritional levels of targeted elements with the effect of their interactions in buffalo calves. Twenty male Murrah buffalo calves of about 8–9 months (bodyweight 112.1 ± 7.69 kg) were distributed into four groups of five calves in each group and fed either a control (C) diet or supplemented with supranutritional levels of Cu ($ T_{1} $), Se ($ T_{2} $), or combination of both ($ T_{3} $) for 120 days. Higher (P = 0.015) values of packed cell volume were observed in group $ T_{2} $ at day 120; otherwise, all other hematological parameters remained comparable among groups. Over the period (day 120 vs. day 0), an enhancement in the percentage of lymphocytes (P = 0.006) with a reduction in neutrophils (P = 0.028) and hemoglobin (P = 0.024) values was observed in the control group. An enhancement in the percentage of monocytes (P = 0.031), with a reduced percentage of neutrophils (P = 0.022), was reported in groups $ T_{2} $ and $ T_{3} $, respectively. Interaction of Cu and Se at supranutritional level (T3) dramatically reduced plasma Cu (P = 0.008) level against the control values, with an improvement in Se markers (i.e., plasma Se, P = 0.041 and enzyme glutathione peroxidase, P = 0.057) over the values in calves fed supplemental Se alone ($ T_{2} $). Additionally, Cu ($ T_{1} $ and $ T_{3} $) was forced to decline (P < 0.05) Zn level in the plasma of buffalo calves. Cu ($ T_{1} $, P < 0.05) and Se ($ T_{2} $ and $ T_{3} $, P ≤ 0.01) supplementation was able to improve their respective plasma levels. The interaction of two trace elements at the supranutritional level further helped in reducing the lipid peroxidation (P = 0.01) values as well. Though antioxidant vitamins and cell-mediated immunity remained unaffected, humoral immunity against antigen P. multocida was high (P = 0.005) in the group $ T_{2} $. The conclusion may be drawn that supranutritional Cu and Se were capable to influence certain blood parameters with an additional interaction effect due to simultaneous supplementation in buffalo calves. | ||
| 650 | 4 | |a Antioxidant profile | |
| 650 | 4 | |a Buffalo calves | |
| 650 | 4 | |a Copper | |
| 650 | 4 | |a Hematology | |
| 650 | 4 | |a Immunity | |
| 650 | 4 | |a Selenium | |
| 700 | 1 | |a Garg, Anil Kumar |4 aut | |
| 700 | 1 | |a Dass, Ram Sharan |4 aut | |
| 700 | 1 | |a Rawat, Mayank |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Biological trace element research |d Springer US, 1979 |g 201(2022), 1 vom: 29. Jan., Seite 156-169 |w (DE-627)130077275 |w (DE-600)445336-0 |w (DE-576)015614395 |x 0163-4984 |7 nnns |
| 773 | 1 | 8 | |g volume:201 |g year:2022 |g number:1 |g day:29 |g month:01 |g pages:156-169 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s12011-022-03122-9 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a FID-BIODIV | ||
| 912 | |a SSG-OLC-CHE | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a SSG-OLC-DE-84 | ||
| 951 | |a AR | ||
| 952 | |d 201 |j 2022 |e 1 |b 29 |c 01 |h 156-169 | ||