Serological and molecular investigation of 2117-like vesiviruses in cats
Abstract Vesivirus 2117 was first discovered as a contaminant in Chinese hamster ovary (CHO) cell cultures used for human drug production. Similar vesiviruses (VeVs) have been detected recently in dogs. In order to address the hypothesis that cats may also be exposed to 2117-like VeVs, in this study, we screened 236 feline sera using an enzyme-linked immunosorbent assay (ELISA) based on a recombinant VP1 protein from the canine VeV Bari/212/07/ITA. IgG antibodies against the 2117-like VeV were detected in 37.3% of the sera tested. Also, by screening cat faecal specimens, the RNA of a 2117-like VeV was detected in a clinically healthy cat..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:163 |
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| Enthalten in: |
Archives of virology - 163(2017), 1 vom: 11. Okt., Seite 197-201 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Di Martino, Barbara [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Anmerkungen: |
© Springer-Verlag GmbH Austria 2017 |
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| doi: |
10.1007/s00705-017-3582-z |
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OLC2057035700 |
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| 520 | |a Abstract Vesivirus 2117 was first discovered as a contaminant in Chinese hamster ovary (CHO) cell cultures used for human drug production. Similar vesiviruses (VeVs) have been detected recently in dogs. In order to address the hypothesis that cats may also be exposed to 2117-like VeVs, in this study, we screened 236 feline sera using an enzyme-linked immunosorbent assay (ELISA) based on a recombinant VP1 protein from the canine VeV Bari/212/07/ITA. IgG antibodies against the 2117-like VeV were detected in 37.3% of the sera tested. Also, by screening cat faecal specimens, the RNA of a 2117-like VeV was detected in a clinically healthy cat. | ||
| 700 | 1 | |a Di Profio, Federica |4 aut | |
| 700 | 1 | |a Melegari, Irene |4 aut | |
| 700 | 1 | |a Sarchese, Vittorio |4 aut | |
| 700 | 1 | |a Massirio, Ivano |4 aut | |
| 700 | 1 | |a Luciani, Alessia |4 aut | |
| 700 | 1 | |a Lanave, Gianvito |4 aut | |
| 700 | 1 | |a Marsilio, Fulvio |4 aut | |
| 700 | 1 | |a Martella, Vito |4 aut | |
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