Parenteral fluoroquinolones in children with life-threatening infections
Summary The new fluoroquinolones have not been tested in children despite their wide spectrum ofin vitro activity and efficacy, because of an observed damage to cartilage in young animals. However, in some cases they may be life-saving. We present three pediatric patients with life threatening infections in whom the fluoroquinolones were used when other antibiotics failed: A seven-year-old boy with meningitis due to multiresistantAcinetobacter calcoaceticus, a three-year-old boy with Job's syndrome with line sepsis due toStaphylococcus epidermidis and a four month-old boy with agammaglobulinemia with mixed infection due toEscherichia coli, Pseudomonas aeruginosa, andAcinetobacter spp. All three children were cured of their infections..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1990 |
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| Erschienen: |
1990 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:18 |
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| Enthalten in: |
Infection - 18(1990), 4 vom: Juli, Seite 237-238 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dagan, R. [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
Fluoroquinolones |
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| Anmerkungen: |
© MMV Medizin Verlag GmbH Müncher 1990 |
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| doi: |
10.1007/BF01643396 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2051818185 |
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| 245 | 1 | 0 | |a Parenteral fluoroquinolones in children with life-threatening infections |
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| 520 | |a Summary The new fluoroquinolones have not been tested in children despite their wide spectrum ofin vitro activity and efficacy, because of an observed damage to cartilage in young animals. However, in some cases they may be life-saving. We present three pediatric patients with life threatening infections in whom the fluoroquinolones were used when other antibiotics failed: A seven-year-old boy with meningitis due to multiresistantAcinetobacter calcoaceticus, a three-year-old boy with Job's syndrome with line sepsis due toStaphylococcus epidermidis and a four month-old boy with agammaglobulinemia with mixed infection due toEscherichia coli, Pseudomonas aeruginosa, andAcinetobacter spp. All three children were cured of their infections. | ||
| 650 | 4 | |a Pseudomonas | |
| 650 | 4 | |a Meningitis | |
| 650 | 4 | |a Pediatric Patient | |
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| 700 | 1 | |a Einhorn, M. |4 aut | |
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