Synthesis, anti-inflammatory and antinociceptive activity of some novel benzothiazole derivatives
Abstract A new series of derivatives bearing benzothiazol-2-one or benzothiazole ring system conjugated to other different heterocycles were prepared using 5,6-dimethoxy-3-benzothiazol-2(3H)-one (1) as a starting material. The structures of the newly synthesized products have been established based on analytical and spectral data. In addition, the anti-inflammatory and antinociceptive activities of some of the products were evaluated. Our data showed that many derivatives have promising activities as anti-inflammatory and antinocicepative agents..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2013 |
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| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:41 |
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| Enthalten in: |
Research on chemical intermediates - 41(2013), 4 vom: 07. Sept., Seite 2537-2555 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Abbas, Eman M. H. [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
Anti-inflammatory |
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| Anmerkungen: |
© Springer Science+Business Media Dordrecht 2013 |
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| doi: |
10.1007/s11164-013-1367-x |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC204207618X |
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| 520 | |a Abstract A new series of derivatives bearing benzothiazol-2-one or benzothiazole ring system conjugated to other different heterocycles were prepared using 5,6-dimethoxy-3-benzothiazol-2(3H)-one (1) as a starting material. The structures of the newly synthesized products have been established based on analytical and spectral data. In addition, the anti-inflammatory and antinociceptive activities of some of the products were evaluated. Our data showed that many derivatives have promising activities as anti-inflammatory and antinocicepative agents. | ||
| 650 | 4 | |a Benzothiazol-2-one | |
| 650 | 4 | |a Benzothiazole | |
| 650 | 4 | |a Anti-inflammatory | |
| 650 | 4 | |a Antinocicepative | |
| 700 | 1 | |a Amin, Kamelia M. |4 aut | |
| 700 | 1 | |a El-Hamouly, Wageeh S. |4 aut | |
| 700 | 1 | |a Dawood, Dina H. |4 aut | |
| 700 | 1 | |a Abdalla, Mohamed M. |4 aut | |
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